Since the first outbreak in the 19th century influenza virus has remained emergent owing to
the huge pandemic potential. Only the pandemic of 1918 caused more deaths than any war …

The complexity of influenza A virus (IAV) infections in avian hosts leads to equally complex
scenarios for the vaccination of poultry. Vaccination against avian influenza strains can be …

Background Antigenic similarity between vaccine viruses and circulating viruses is crucial
for achieving high vaccine effectiveness against seasonal influenza. New non-egg-based …

Background The implementation of mRNA vaccines against COVID-19 has successfully
validated the safety and efficacy of the platform, while at the same time revealing the …

Vaccines stand as one of the most significant medical advancements, playing a crucial role
in the prevention of infectious diseases and the improvement of global health. The triumph of …

Influenza vaccines faced significant challenges in achieving sufficient protective efficacy and
production efficiency in the past. In recent decades, novel influenza vaccines, characterized …

Influenza A viruses (IAVs), which belong to the Orthomyxoviridae family, are RNA viruses
characterized by a segmented genome that allows them to evolve and adapt rapidly. These …

Affinity-matured plasma cells (PCs) of varying lifespans are generated through a germinal
center (GC) response. The developmental dynamics and genomic programs of antigen …

Partendo da quella che possiamo definire la filosofia della professione, appare evidente
che, nell'ambito della prevenzione vaccinale, il Medico di Medicina Generale (MMG) …

Influenza, a contagious respiratory illness, spreads easily via contaminated surfaces and air.
In majority of the cases, the symptoms are minor, including fever, fatigue, chills, and runny …