[HTML][HTML] Free fatty acid receptors in health and disease
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …
[HTML][HTML] The lung microbiome: progress and promise
SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …
[HTML][HTML] Lung microbiome: new insights into the pathogenesis of respiratory diseases
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …
Microbiome effects on immunity, health and disease in the lung
Chronic respiratory diseases, including asthma, chronic obstructive pulmonary disease
(COPD) and cystic fibrosis (CF), are among the leading causes of mortality and morbidity …
(COPD) and cystic fibrosis (CF), are among the leading causes of mortality and morbidity …
Azithromycin: the first broad-spectrum therapeutic
A Firth, P Prathapan - European journal of medicinal chemistry, 2020 - Elsevier
Abstract The Strategic Plan for Biodefense Research by the US Department of Health and
Human Services demarcates the need for drugs which target multiple types of pathogens to …
Human Services demarcates the need for drugs which target multiple types of pathogens to …
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis
Although destructive airway disease is evident in young children with cystic fibrosis (CF),
little is known about the nature of the early CF lung environment triggering the disease. To …
little is known about the nature of the early CF lung environment triggering the disease. To …
Short Chain Fatty Acids: Fundamental mediators of the gut-lung axis and their involvement in pulmonary diseases
S Ashique, G De Rubis, E Sirohi, N Mishra… - Chemico-biological …, 2022 - Elsevier
The human microbiota is fundamental to correct immune system development and balance.
Dysbiosis, or microbial content alteration in the gut and respiratory tract, is associated with …
Dysbiosis, or microbial content alteration in the gut and respiratory tract, is associated with …
[HTML][HTML] Azithromycin for COVID-19: more than just an antimicrobial?
The COVID-19 infection due to severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is a major public health issue worldwide, as no vaccines or drugs for prevention and …
CoV-2) is a major public health issue worldwide, as no vaccines or drugs for prevention and …
Microbiology of cystic fibrosis airway disease
AC Blanchard, VJ Waters - Seminars in respiratory and critical …, 2019 - thieme-connect.com
Although survival of individuals with cystic fibrosis (CF) has been continuously improving for
the past 40 years, respiratory failure secondary to recurrent pulmonary infections remains …
the past 40 years, respiratory failure secondary to recurrent pulmonary infections remains …
[HTML][HTML] Metabolism meets immunity: The role of free fatty acid receptors in the immune system
E Alvarez-Curto, G Milligan - Biochemical pharmacology, 2016 - Elsevier
There are significant numbers of nutrient sensing G protein-coupled receptors (GPCRs) that
can be found in cells of the immune system and in tissues that are involved in metabolic …
can be found in cells of the immune system and in tissues that are involved in metabolic …