The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix
ligands, cell-surface ligands, and soluble ligands. They are transmembrane αβ heterodimers …

The ADAMs (a disintegrin and metalloproteinase) are a fascinating family of transmembrane
and secreted proteins with important roles in regulating cell phenotype via their effects on …

The ADAMs family of transmembrane proteins belongs to the zinc protease superfamily.
Members of the family have a modular design, characterized by the presence of …

ADAMs contain adhesive and metalloprotease domains. As major ectodomain sheddases,
they release a variety of cell-surface proteins, including growth factors, cytokines, cell …

Human cytomegalovirus (HCMV) is capable of manifesting disease in nearly every organ
system in immunocompromised patients. This broad pathogenic tropism correlates with the …

Human cytomegalovirus (HCMV), a dsDNA, enveloped virus, is a ubiquitous pathogen that
establishes lifelong latent infections and caused disease in persons with compromised …

For more than half a century, cytotoxic agents have been investigated as a possible
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …

Fertilization is the fusion of the male and female gamete. The process involves the fusion of
an oocyte with a sperm, creating a single diploid cell, the zygote, from which a new …

Viruses successfully infect host cells by initially binding to the surfaces of the cells, followed
by an intricate entry process. As multifunctional heterodimeric cell-surface receptor …

A disintegrin and metalloproteinases (ADAMs) are a recently discovered family of proteins
that share the metalloproteinase domain with matrix metalloproteinases (MMPs). Among this …