Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many
living organisms. In human beings, pineal gland is the major site for melatonin production …

Melatonin is an ancient molecule that can be traced back to the origin of life. Melatonin's
initial function was likely that as a free radical scavenger. Melatonin presumably evolved in …

Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at
night under normal light/dark conditions. The endogenous rhythm of secretion is generated …

Endogenous melatonin is synthesized from tryptophan via 5-hydroxytryptamine. It is
considered an indoleamine from a biochemical point of view because the melatonin …

Melatonin, a multifunctional signaling molecule, is ubiquitously distributed in different parts
of a plant and responsible for stimulating several physiochemical responses against …

Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …

The pineal gland is a unique organ that synthesizes melatonin as the signaling molecule of
natural photoperiodic environment and as a potent neuronal protective antioxidant. An intact …

Free radicals generated within subcellular compartments damage macromolecules which
lead to severe structural changes and functional alterations of cellular organelles. A …

Excess weight and obesity are severe public health threats worldwide. Recent evidence
demonstrates that gut microbiota dysbiosis contributes to obesity and its comorbidities. The …

A comprehensive investigation was carried out to determine the changes that occurred in
water‐stressed cucumber (Cucumis sativus L.) in response to melatonin treatment. We …