Oxidative stress, free radicals and antioxidants: Potential crosstalk in the pathophysiology of human diseases

P Chaudhary, P Janmeda, AO Docea… - Frontiers in …, 2023 - frontiersin.org
Introduction: Free radicals are reactive oxygen species that constantly circulate through the
body and occur as a side effect of many reactions that take place in the human body. Under …

COVID-19 and oxidative stress

BV Chernyak, EN Popova, AS Prikhodko… - Biochemistry …, 2020 - Springer
Pathogenesis of the novel coronavirus infection COVID-19 is the subject of active research
around the world. COVID-19 caused by the SARS-CoV-2 is a complex disease in which …

Quercetin prevents LPS-induced oxidative stress and inflammation by modulating NOX2/ROS/NF-kB in lung epithelial cells

OJ Sul, SW Ra - Molecules, 2021 - mdpi.com
Oxidative stress caused by the production of reactive oxygen species (ROS) plays a major
role in inflammatory processes. We hypothesized that modulation of ROS via quercetin may …

Oxidative stress in COPD

PA Kirkham, PJ Barnes - Chest, 2013 - Elsevier
Oxidative stress is now recognized as a major predisposing factor in the pathogenesis of
COPD. Existing therapies for COPD are ineffective at halting disease progression, with …

Advances in metal-induced oxidative stress and human disease

K Jomova, M Valko - Toxicology, 2011 - Elsevier
Detailed studies in the past two decades have shown that redox active metals like iron (Fe),
copper (Cu), chromium (Cr), cobalt (Co) and other metals undergo redox cycling reactions …

Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of Controlled Release, 2020 - Elsevier
Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

The role of oxidative stress in the pathogenesis of infections with coronaviruses

C Gain, S Song, T Angtuaco, S Satta… - Frontiers in …, 2023 - frontiersin.org
Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

Natural products as home‐based prophylactic and symptom management agents in the setting of COVID‐19

SM Thota, V Balan… - Phytotherapy …, 2020 - Wiley Online Library
Coronavirus disease (COVID‐19) caused by the novel coronavirus (SARS‐CoV‐2) has
rapidly spread across the globe affecting 213 countries or territories with greater than six …

Inflammatory and oxidative responses induced by exposure to commonly used e-cigarette flavoring chemicals and flavored e-liquids without nicotine

T Muthumalage, M Prinz, KO Ansah, J Gerloff… - Frontiers in …, 2018 - frontiersin.org
Background: The respiratory health effects of inhalation exposure to e-cigarette flavoring
chemicals are not well understood. We focused our study on the immuno-toxicological and …

Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases

IT Lee, CM Yang - Biochemical pharmacology, 2012 - Elsevier
Reactive oxygen species (ROS) are products of normal cellular metabolism and are known
to act as second messengers. Under physiological conditions, ROS participate in …