Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are suggested to be
responsible for drug resistance and cancer relapse due in part to their ability to self‐renew …

Despite the abundant ongoing research efforts, cancer remains one of the most challenging
diseases to treat globally. Due to the heterogenous nature of cancer, one of the major …

One of the current stumbling blocks in our fight against cancer is the development of
acquired resistance to therapy, which is attributable to approximately 90% of cancer-related …

Breast cancer remains to be a dreadful disease even with several advancements in
radiation and chemotherapies, owing to the drug resistance and tumor relapse caused by …

The cancer stem cell (CSC) hypothesis, despite the limitations of the currently available
models and assays, has ushered in a new era of excitement in cancer research. The …

Expression of the membrane protein CD133 marks a subset of cancer cells with drug
resistant phenotype and enhanced tumor initiating ability in xenotransplantation assays …

Cancer stem cells (CSCs) represent a small subset of tumor cells which have the ability to
self-renew and generate the diverse cells that comprise the tumor bulk. They are …

Objectives While most women with ovarian cancer will achieve complete remission after
treatment, the majority will relapse within two years, highlighting the need for novel …

Background Natural killer (NK) cells are potent cytotoxic lymphocytes that play a critical role
in tumor immunosurveillance and control. Cancer stem cells (CSC) initiate and sustain tumor …

Cancer stem cells (CSC) are capable of promoting tumor initiation and self-renewal, two
important hallmarks of carcinoma formation. This population comprises a small percentage …