The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

A Kadioglu, JN Weiser, JC Paton… - Nature Reviews …, 2008 - nature.com
Streptococcus pneumoniae is a Gram-positive bacterial pathogen that colonizes the
mucosal surfaces of the host nasopharynx and upper airway. Through a combination of …

Streptococcus pneumoniae: virulence factors, pathogenesis, and vaccines

E AlonsoDeVelasco, AF Verheul, J Verhoef… - Microbiological …, 1995 - Am Soc Microbiol
Although pneumococcal conjugate vaccines are close to being licensed, a more profound
knowledge of the virulence factors responsible for the morbidity and mortality caused by …

Association of Intrastrain Phase Variation in Quantity of Capsular Polysaccharide and Teichoic Acid with the Virulence of Streptococcus pneumoniae

JO Kim, JN Weiser - Journal of Infectious Diseases, 1998 - academic.oup.com
The pneumococcus undergoes spontaneous phase variation between an opaque and a
transparent colony form. In an animal model of systemic infection following intraperitoneal …

CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization

R Malley, K Trzcinski, A Srivastava… - Proceedings of the …, 2005 - National Acad Sciences
Acquired immunity to Streptococcus pneumoniae (pneumococcus) has long been assumed
to depend on the presence of anticapsular antibodies. We found, however, that colonization …

[图书][B] An introduction to polysaccharide biotechnology

SE Harding, MP Tombs, GG Adams, BS Paulsen… - 2017 - taylorfrancis.com
Polysaccharides and related high molecular weight glycans are hugely diverse with wide
application in Biotechnology and great opportunities for further exploitation. An Introduction …

Description of 14 new capsular types of Streptococcus suis

M Gottschalk, R Higgins, M Jacques… - Journal of clinical …, 1989 - Am Soc Microbiol
Fourteen new capsular types of Streptococcus suis (types 9 to 22) are described. All
reference strains are morphologically and biochemically similar to types previously …

[HTML][HTML] Vaccines based on the cell surface carbohydrates of pathogenic bacteria

C Jones - Anais da Academia Brasileira de Ciencias, 2005 - SciELO Brasil
Glycoconjugate vaccines, in which a cell surface carbohydrate from a micro-organism is
covalently attached to an appropriate carrier protein are proving to be the most effective …

A visual review of the human pathogen Streptococcus pneumoniae

DH Engholm, M Kilian, DS Goodsell… - FEMS microbiology …, 2017 - academic.oup.com
Being the principal causative agent of bacterial pneumonia, otitis media, meningitis and
septicemia, the bacterium Streptococcus pneumoniae is a major global health problem. To …

Teichoic acid and lipoteichoic acid of Streptococcus pneumoniae possess identical chain structures: A reinvestigation of teichoid acid (C polysaccharide)

W Fischer, T Behr, R Hartmann… - European journal of …, 1993 - Wiley Online Library
Teichoic acid (C polysaccharide) was extracted and purified from Streptococcus
pneumoniae R6 with standard procedures except that lipoteichoic acid was extracted first …

Effect of capsulation of opportunistic pathogenic bacteria on binding of the pattern recognition molecules mannan-binding lectin, L-ficolin, and H-ficolin

A Krarup, UBS Sørensen, M Matsushita… - Infection and …, 2005 - Am Soc Microbiol
ABSTRACT Mannan-binding lectin (MBL), L-ficolin, and H-ficolin are pattern recognition
molecules of the innate immune system. We investigated their ability to bind to different …