Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique offering profound
insights into a broad spectrum of biological processes such as metabolic imaging, protein …

Background Optimal detection and surveillance of bladder cancer (BCa) rely primarily on the
cystoscopic visualization of bladder lesions. AI-assisted cystoscopy may improve image …

Reproductive aging in female mammals is an irreversible process associated with declining
oocyte quality, which is the rate-limiting factor to fertility. Here, we show that this loss of …

Although breast cancer stem cells (BCSCs) display plasticity transitioning between
quiescent mesenchymal-like (M) and proliferative epithelial-like (E) states, how this plasticity …

Stem cells reside in specialized niches that are critical for their function. Upon activation, hair
follicle stem cells (HFSCs) exit their niche to generate the outer root sheath (ORS), but a …

Label-free imaging through two-photon autofluorescence of NAD (P) H allows for
nondestructive, high-resolution visualization of cellular activities in living systems. However …

The function of macrophages in vitro is linked to their metabolic rewiring. However,
macrophage metabolism remains poorly characterized in situ. Here, we used two-photon …

Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …

The preparation of highly modified mRNAs and visualization of their cellular distribution are
challenging. We report in-cell application of in vitro transcribed mRNA containing natural …

Redox reactions are of high fundamental and practical interest since they are involved in
both normal physiology and the pathogenesis of various diseases. However, this area of …