Cochlear motion across the reticular lamina implies that it is not a stiff plate

NH Cho, S Puria - Scientific Reports, 2022 - nature.com
Within the cochlea, the basilar membrane (BM) is coupled to the reticular lamina (RL)
through three rows of piezo-like outer hair cells (OHCs) and supporting cells that endow …

Development of ultrasensitive biomimetic auditory hair cells based on piezoresistive hydrogel nanocomposites

H Ahmadi, H Moradi, CJ Pastras… - … applied materials & …, 2021 - ACS Publications
With an ageing population, hearing disorders are predicted to rise considerably in the
following decades. Thus, developing a new class of artificial auditory system has been …

Cochlear amplification in the short-wave region by outer hair cells changing organ-of-Corti area to amplify the fluid traveling wave

JJ Guinan Jr - Hearing Research, 2022 - Elsevier
Many details of the operation of the mammalian cochlea are known, but how they all work
together to produce cochlear amplification is not understood. Outer-hair-cell (OHC) motility …

Reconstruction of transverse-longitudinal vibrations in the organ of Corti complex via optical coherence tomography

BL Frost, CE Strimbu, ES Olson - The Journal of the Acoustical Society …, 2023 - pubs.aip.org
Optical coherence tomography (OCT) is a common modality for measuring vibrations within
the organ of Corti complex (OCC) in vivo. OCT's uniaxial nature leads to limitations that …

Electrocochleography-Based Tonotopic Map: I. Place Coding of the Human Cochlea With Hearing Loss

A Walia, AJ Ortmann, S Lefler, TA Holden… - Ear and …, 2025 - journals.lww.com
Objectives: Due to the challenges of direct in vivo measurements in humans, previous
studies of cochlear tonotopy primarily utilized human cadavers and animal models. This …

Salicylate-induced changes in organ of Corti vibrations

CE Strimbu, ES Olson - Hearing research, 2022 - Elsevier
Intra organ of Corti (OC) vibrations differ from those measured at the basilar membrane
(BM), with higher amplitudes and a wide-band nonlinearity extending well below a region's …

Corti fluid is a medium for outer hair cell force transmission

M Shokrian, WC Lin, A Macić, JH Nam - Journal of Neuroscience, 2025 - jneurosci.org
The mammalian cochlea amplifies sounds selectively to improve frequency resolution.
However, vibrations around the outer hair cells (OHCs) are amplified nonselectively. The …

Motion of the cochlear reticular lamina varies radially across outer-hair-cell rows

NH Cho, S Puria - bioRxiv, 2022 - biorxiv.org
The basilar membrane (BM) is connected to the reticular lamina (RL) through three rows of Y-
shaped structures consisting of an outer hair cell (OHC) and a Deiters' cell (DC) with a …

The Origin Along the Cochlea of Otoacoustic Emissions Evoked by Mid-Frequency Tone Pips

SS Goodman, SM Lefler, C Lee, JJ Guinan Jr… - Journal of the …, 2024 - Springer
Purpose Tone-pip-evoked otoacoustic emissions (PEOAEs) are transient-evoked
otoacoustic emissions (OAEs) that are hypothesized to originate from reflection of energy …

Toward personalized diagnosis and therapy for hearing loss: insights from Cochlear implants

V Sagi, KM Stankovic - Otology & Neurotology, 2022 - journals.lww.com
Sensorineural hearing loss (SNHL) is the most common sensory deficit, disabling nearly half
a billion people worldwide. The cochlear implant (CI) has transformed the treatment of …