Anelloviruses versus human immunity: how do we control these viruses?

AL Timmerman, ALM Schönert… - FEMS microbiology …, 2024 - academic.oup.com
One continuous companion and one of the major players in the human blood virome are
members of the Anelloviridae family. Anelloviruses are probably found in all humans …

[HTML][HTML] TTV and other anelloviruses: the astonishingly wide spread of a viral infection

PG Spezia, D Focosi, A Baj, F Novazzi… - Aspects of Molecular …, 2023 - Elsevier
The broad family of viruses known as anelloviruses (AV) infects both humans and numerous
animal species. They have a tiny, covalently closed single-stranded DNA genome and the …

The Impact of First-Time SARS-CoV-2 Infection on Human Anelloviruses

AL Timmerman, L Commandeur, M Deijs… - Viruses, 2024 - mdpi.com
Members of the Anelloviridae family dominate the blood virome, emerging early in life. The
anellome, representing the variety of anelloviruses within an individual, stabilizes by …

Anellovirus structure reveals a mechanism for immune evasion

S Liou, N Cohen, Y Zhang, NM Acharekar, H Rodgers… - Biorxiv, 2022 - biorxiv.org
The significant impact of the human virome on human physiology is beginning to emerge
thanks to modern sequencing methods and bioinformatic tools. Anelloviruses, the principal …

Control of human anelloviruses by cytosine to uracil genome editing

AL Timmerman, J Kaczorowska, M Deijs, M Bakker… - Msphere, 2022 - Am Soc Microbiol
Anelloviruses are the most common viruses infecting humans. Every human carries a
nonpathogenic personal anellovirus virome (anellome), yet it is unknown which …

Exploring immunome and microbiome interplay in reproductive health: current knowledge, challenges, and novel diagnostic tools

P Lingasamy, V Modhukur, R Mändar… - Seminars in …, 2024 - thieme-connect.com
The dynamic interplay between the immunome and microbiome in reproductive health is a
complex and rapidly advancing research field, holding tremendously vast possibilities for the …

Anellovirus evolution during long-term chronic infection

J Kaczorowska, AL Timmerman, M Deijs… - Virus …, 2023 - academic.oup.com
Human anelloviruses (AVs) are extremely genetically diverse, are widespread in the human
population, and cause chronic infections. However, the evolutionary dynamics of AVs within …

Comprehensive phage display viral antibody profiling using VirScan: potential applications in chronic immune-mediated disease

JV Shrewsbury, ES Vitus, AL Koziol… - Journal of …, 2024 - journals.asm.org
ABSTRACT Phage immunoprecipitation sequencing (PhIP-Seq) is a high-throughput
platform that uses programmable phage display for serology. VirScan, a specific PhIP-Seq …

[HTML][HTML] The Blood Virome: A new frontier in biomedical science

AJ Kandathil, DL Thomas - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Recent advances in metagenomic testing opened a new window into the mammalian blood
virome. Comprised of well-known viruses like human immunodeficiency virus, hepatitis C …

[HTML][HTML] Phage immunoprecipitation and sequencing—a versatile technique for mapping the antibody reactome

GN Sundell, SC Tao - Molecular & Cellular Proteomics, 2024 - Elsevier
Characterizing the antibody reactome for circulating antibodies provide insight into
pathogen exposure, allergies and autoimmune diseases. This is important for biomarker …