The global burden of coeliac disease: opportunities and challenges
Coeliac disease is a systemic disorder characterized by immune-mediated enteropathy,
which is caused by gluten ingestion in genetically susceptible individuals. The clinical …
which is caused by gluten ingestion in genetically susceptible individuals. The clinical …
Current and emerging therapies for coeliac disease
L Kivelä, A Caminero, DA Leffler… - Nature reviews …, 2021 - nature.com
Coeliac disease is a common enteropathy that occurs in genetically susceptible individuals
in response to the ingestion of gluten proteins present in wheat, rye and barley. Currently …
in response to the ingestion of gluten proteins present in wheat, rye and barley. Currently …
Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial
L Krogvold, IM Mynarek, E Ponzi, FB Mørk… - Nature Medicine, 2023 - nature.com
Previous studies showed a low-grade enterovirus infection in the pancreatic islets of patients
with newly diagnosed type 1 diabetes (T1D). In the Diabetes Virus Detection (DiViD) …
with newly diagnosed type 1 diabetes (T1D). In the Diabetes Virus Detection (DiViD) …
Effect of gluten-free diet on gut microbiota composition in patients with celiac disease and non-celiac gluten/wheat sensitivity
Celiac disease (CD) and non-celiac gluten/wheat sensitivity (NCG/WS) are the two most
frequent conditions belonging to gluten-related disorders (GRDs). Both these diseases are …
frequent conditions belonging to gluten-related disorders (GRDs). Both these diseases are …
Wheat/gluten-related disorders and gluten-free diet misconceptions: A review
In the last 10,000 years, wheat has become one of the most important cereals in the human
diet and today, it is widely consumed in many processed food products. Mostly considered a …
diet and today, it is widely consumed in many processed food products. Mostly considered a …
T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease
The human leukocyte antigen (HLA) locus is strongly associated with T cell-mediated
autoimmune disorders. HLA-DQ2. 5-mediated celiac disease (CeD) is triggered by the …
autoimmune disorders. HLA-DQ2. 5-mediated celiac disease (CeD) is triggered by the …
Enteroviruses and type 1 diabetes: multiple mechanisms and factors?
RE Lloyd, M Tamhankar… - Annual review of medicine, 2022 - annualreviews.org
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by insulin deficiency
and resultant hyperglycemia. Complex interactions of genetic and environmental factors …
and resultant hyperglycemia. Complex interactions of genetic and environmental factors …
Immunopathogenesis and environmental triggers in coeliac disease
A Levescot, G Malamut, N Cerf-Bensussan - Gut, 2022 - gut.bmj.com
Coeliac disease (CD) is a frequent immune enteropathy induced by gluten in genetically
predisposed individuals. Its pathogenesis has been extensively studied and CD has …
predisposed individuals. Its pathogenesis has been extensively studied and CD has …
Role of the gut microbiota in the pathogenesis of coeliac disease and potential therapeutic implications
Purpose Although genetic predisposition and exposure to dietary gluten are considered
necessary triggers for the development of coeliac disease, alterations in the gut microbial …
necessary triggers for the development of coeliac disease, alterations in the gut microbial …