Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
Extracellular vesicles as personalized medicine
Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …
intercellular communication network that contributes to health and disease. The contents of …
Mesenchymal stem cell‐derived extracellular vesicles with high PD‐L1 expression for autoimmune diseases treatment
Autoimmune diseases are the third most common disease influencing the quality of life of
many patients. Here, a programmed cell death‐ligand 1+(PD‐L1) mesenchymal stem cell …
many patients. Here, a programmed cell death‐ligand 1+(PD‐L1) mesenchymal stem cell …
Engineered extracellular vesicles with SHP2 high expression promote mitophagy for Alzheimer's disease treatment
Mitochondrial dysfunction is a fundamental pathological feature of Alzheimer's disease (AD).
However, toxicity and poor brain enrichment of existing mitophagy inducers limit their further …
However, toxicity and poor brain enrichment of existing mitophagy inducers limit their further …
Extracellular vesicles protect the neonatal lung from hyperoxic injury through the epigenetic and transcriptomic reprogramming of myeloid cells
Rationale: Mesenchymal stem/stromal cell (MSC)–small extracellular vesicle (MEx)
treatment has shown promise in experimental models of neonatal lung injury. The molecular …
treatment has shown promise in experimental models of neonatal lung injury. The molecular …
Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases
J Zhu, S Wang, D Yang, W Xu, H Qian - Journal of Nanobiotechnology, 2023 - Springer
Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …
Mesenchymal stromal cell extracellular vesicles as therapy for acute and chronic respiratory diseases: A meta‐analysis
Preclinical studies suggest mesenchymal stromal cell extracellular vesicles (MSC‐EVs)
reduce inflammation and improve organ function in lung diseases; however, an objective …
reduce inflammation and improve organ function in lung diseases; however, an objective …
The role of exosome and the ESCRT pathway on enveloped virus infection
Y Ju, H Bai, L Ren, L Zhang - International Journal of Molecular Sciences, 2021 - mdpi.com
The endosomal sorting complex required for transport (ESCRT) system consists of
peripheral membrane protein complexes ESCRT-0,-I,-II,-III VPS4-VTA1, and ALIX …
peripheral membrane protein complexes ESCRT-0,-I,-II,-III VPS4-VTA1, and ALIX …
Mesenchymal stem cell-derived extracellular vesicles prevent experimental bronchopulmonary dysplasia complicated by pulmonary hypertension
M Sharma, MA Bellio, M Benny… - Stem cells …, 2022 - academic.oup.com
Mesenchymal stem cell (MSC) extracellular vesicles (EVs) have beneficial effects in
preclinical bronchopulmonary dysplasia and pulmonary hypertension (BPD-PH) models …
preclinical bronchopulmonary dysplasia and pulmonary hypertension (BPD-PH) models …
Stem cell-based therapy for pulmonary fibrosis
W Cheng, Y Zeng, D Wang - Stem Cell Research & Therapy, 2022 - Springer
Pulmonary fibrosis (PF) is a chronic and relentlessly progressive interstitial lung disease in
which the accumulation of fibroblasts and extracellular matrix (ECM) induces the destruction …
which the accumulation of fibroblasts and extracellular matrix (ECM) induces the destruction …