Caloric restriction mimetics against age-associated disease: targets, mechanisms, and therapeutic potential
The increase in life expectancy has boosted the incidence of age-related pathologies
beyond social and economic sustainability. Consequently, there is an urgent need for …
beyond social and economic sustainability. Consequently, there is an urgent need for …
Caffeic acid on metabolic syndrome: A review
Metabolic syndrome (MetS) is a constellation of risk factors that may lead to a more sinister
disease. Raised blood pressure, dyslipidemia in the form of elevated triglycerides and …
disease. Raised blood pressure, dyslipidemia in the form of elevated triglycerides and …
Mesenchymal stem cell-derived exosomes ameliorated diabetic nephropathy by autophagy induction through the mTOR signaling pathway
Background: Diabetic nephropathy (DN) is a serious complication of diabetes mellitus and a
common cause of end-stage renal disease. Autophagy has a defensive role against kidney …
common cause of end-stage renal disease. Autophagy has a defensive role against kidney …
Phenylpropanoids and its derivatives: biological activities and its role in food, pharmaceutical and cosmetic industries
Phenylpropanoids and their derivatives are plant secondary metabolites widely present in
fruits, vegetables, cereal grains, beverages, spices and herbs. They are known to have …
fruits, vegetables, cereal grains, beverages, spices and herbs. They are known to have …
Hydroxycinnamic acids and human health: Recent advances
There is an urgent need to improve human diet globally. Compelling evidence gathered
over the past several decades suggests that a suboptimal diet is associated with many …
over the past several decades suggests that a suboptimal diet is associated with many …
[HTML][HTML] How caffeic acid and its derivatives combat diabetes and its complications: A systematic review
Caffeic acid (CA) and its derivatives, caffeic acid phenyl ethyl amide (CAPA) and caffeic acid
phenyl ester (CAPE), were shown to have anti-oxidant, anti-inflammatory, and anti-diabetic …
phenyl ester (CAPE), were shown to have anti-oxidant, anti-inflammatory, and anti-diabetic …
Hybrid molecules based on caffeic acid as potential therapeutics: A focused review
X Zhao, Z Liu, H Liu, J Guo, S Long - European Journal of Medicinal …, 2022 - Elsevier
Caffeic acid-based compounds possess a high degree of structural diversity and show a
variety of pharmacological properties, providing a useful framework for the discovery of new …
variety of pharmacological properties, providing a useful framework for the discovery of new …
[HTML][HTML] Lycium barbarum L. leaves ameliorate type 2 diabetes in rats by modulating metabolic profiles and gut microbiota composition
X Zhao, S Guo, Y Lu, Y Hua, F Zhang, H Yan… - Biomedicine & …, 2020 - Elsevier
The leaf of Lycium barbarum L.(LLB) has been widely used as a tea, vegetable, and herb in
China and Southeast Asia for centuries; this is because of the hypoglycemic effect it has, but …
China and Southeast Asia for centuries; this is because of the hypoglycemic effect it has, but …
[HTML][HTML] Modulatory effect of caffeic acid in alleviating diabetes and associated complications
R Ganguly, SV Singh, K Jaiswal, R Kumar… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is one of the most common metabolic disorders characterized by
elevated blood glucose levels. Prolonged uncontrolled hyperglycemia often leads to multi …
elevated blood glucose levels. Prolonged uncontrolled hyperglycemia often leads to multi …
Dysregulated autophagy: a key player in the pathophysiology of type 2 diabetes and its complications
Autophagy is essential in regulating the turnover of macromolecules via removing damaged
organelles, misfolded proteins in various tissues, including liver, skeletal muscles, and …
organelles, misfolded proteins in various tissues, including liver, skeletal muscles, and …