Introduction Approximately a third of the population worldwide is chronically infected with
Toxoplasma gondii. Pyrimethamine-based regimens are recommended for the treatment of …

Toxoplasmosis is a common disease caused by Toxoplasma gondii, a parasite with high
prevalence in tropical regions. Most infections show minimal symptoms, but …

A safer treatment for toxoplasmosis would be achieved by improving the selectivity and
potency of dihydrofolate reductase (DHFR) inhibitors, such as pyrimethamine (1), for …

(1) Background: Toxoplasma gondii infects approximately one third of the world's human
population. The seroepidemiology of T. gondii in cardiovascular patients is poorly discussed …

Abstract Purpose of Review Toxoplasmosis is an apicomplexan parasite that can be found
in all countries, which causes an infection of the central nervous system. This review outlines …

CD8 T cells are important for maintaining the chronicity of Toxoplasma gondii infection. In a
T. gondii encephalitis susceptible model, we recently demonstrated that CD4 T cells play an …

This study evaluated the effects of rosuvastatin in vivo on toxoplasmosis chronic infection.
Thirty-five Swiss mice were orally infected (ME-49 strain). After 50 days, the mice were …

Aspartic proteases in the Toxoplasma gondii, called TgASP1, 2, 3, and 5, play essential
roles in the life cycle. In a previous study, we have demonstrated that TgASP1 is an antigen …

Toxoplasma gondii (T. gondii) is a cosmopolitan protozoan parasite in humans and animals.
It infects about 30% of the human population worldwide and causes potentially fatal …

Myocarditis is a rare complication of toxoplasmosis, especially in immunocompetent
individuals. We present a case of a 28-year-old man with a history of fever and chest pain …