Remarkable advances in our understanding of olfactory perception have been made in recent years, including the discovery of new mechanisms of olfactory signaling and new …
Vertebrates and insects have evolved complex repertoires of chemosensory receptors to detect and distinguish odours. With a few exceptions, vertebrate chemosensory receptors …
The mammalian olfactory system senses an almost unlimited number of chemical stimuli and initiates a process of neural recognition that influences nearly every aspect of life. This …
K Matulef, WN Zagotta - Annual review of cell and …, 2003 - annualreviews.org
▪ Abstract Cyclic nucleotide-gated (CNG) ion channels were first discovered in rod photoreceptors, where they are responsible for the primary electrical signal of the …
SJ Kleene - Chemical senses, 2008 - academic.oup.com
Most vertebrate olfactory receptor neurons share a common G-protein–coupled pathway for transducing the binding of odorant into depolarization. The depolarization involves 2 …
M Biel, S Michalakis - cGMP: generators, effectors and therapeutic …, 2009 - Springer
Cyclic nucleotide-gated (CNG) channels are ion channels which are activated by the binding of cGMP or cAMP. The channels are important cellular switches which transduce …
How are sights and sounds and smells converted into electrical signals in a form that can be interpreted by the nervous system? Although this process, called sensory transduction …
Sensory perception requires accurate encoding of stimulus information by sensory receptor cells. We identified NCKX4, a potassium-dependent Na+/Ca2+ exchanger, as being …
M Biel - Journal of Biological Chemistry, 2009 - ASBMB
Cyclic nucleotide-regulated cation channels are ion channels whose activation is regulated by the direct binding of cAMP or cGMP to the channel protein. Two structurally related …