TNFα in atherosclerosis, myocardial ischemia/reperfusion and heart failure

P Kleinbongard, G Heusch, R Schulz - Pharmacology & therapeutics, 2010 - Elsevier
TNFα is crucially involved in the pathogenesis and progression of atherosclerosis,
myocardial ischemia/reperfusion injury and heart failure. The formation and release of TNFα …

Myocardial repair/remodelling following infarction: roles of local factors

Y Sun - Cardiovascular research, 2009 - academic.oup.com
Heart failure is a global health problem, appearing most commonly in patients with previous
myocardial infarction (MI). Cardiac remodelling, particularly fibrosis, seen in both the …

TNFα in myocardial ischemia/reperfusion, remodeling and heart failure

P Kleinbongard, R Schulz, G Heusch - Heart failure reviews, 2011 - Springer
TNFα is crucially involved in the pathogenesis and progression of myocardial
ischemia/reperfusion injury and heart failure. The formation and release of TNFα and its …

Conceptualizing self-care in heart failure: a life course model of patient characteristics

DK Moser, JF Watkins - Journal of cardiovascular nursing, 2008 - journals.lww.com
Self-care is fundamental to achieving optimal outcomes in patients with heart failure.
Unfortunately, self-care among patients with heart failure is commonly poor, and patients …

Nutritional and anti-inflammatory interventions in chronic heart failure

K Kalantar-Zadeh, SD Anker, TB Horwich… - The American journal of …, 2008 - Elsevier
Currently, there are 5 million individuals with chronic heart failure (CHF) in the United States
who have poor clinical outcomes, including high death rates. Observational studies have …

Effects of atorvastatin on reactive hyperemia and inflammatory process in patients with congestive heart failure

D Tousoulis, C Antoniades, E Bosinakou… - Atherosclerosis, 2005 - Elsevier
Purpose of the study was to investigate whether short-term atorvastatin treatment improves
endothelial function and affects inflammatory process in patients with heart failure (HF) and …

Norepinephrine induces apoptosis in neonatal rat cardiomyocytes through a reactive oxygen species–TNFα–caspase signaling pathway

YC Fu, CS Chi, SC Yin, B Hwang… - Cardiovascular …, 2004 - academic.oup.com
Abstract Objective: Norepinephrine (NE)-induced apoptosis in cardiomyocytes is an
important cause of heart failure. Previous studies revealed that reactive oxygen species …

Effects of combined administration of low dose atorvastatin and vitamin E on inflammatory markers and endothelial function in patients with heart failure

D Tousoulis, C Antoniades… - European journal of …, 2005 - Wiley Online Library
Background: Heart failure has been associated with impaired endothelial function,
increased inflammatory process and elevated oxidative stress status. Both statins and …

Levosimendan: beyond its simple inotropic effect in heart failure

C Antoniades, D Tousoulis, N Koumallos… - Pharmacology & …, 2007 - Elsevier
Classic inotropic agents provide short-term haemodynamic improvement in patients with
heart failure, but their use has been associated with poor prognosis. A new category of …

Tumour necrosis factor alpha and the cardiovascular system: its role in cardiac allograft rejection and heart disease

M Azzawi, P Hasleton - Cardiovascular research, 1999 - academic.oup.com
1. Introduction of cytokines, adhesion molecules, and inducible nitric oxide synthase (iNOS).
TNFα has many proinflammatory Tumour necrosis factor alpha (TNFα) is a pleiotropic …