A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: prevalence, severity and impact on quality of life

SB Jensen, AML Pedersen, A Vissink… - Supportive care in …, 2010 - Springer
Purpose This systematic review aimed to assess the literature for prevalence, severity, and
impact on quality of life of salivary gland hypofunction and xerostomia induced by cancer …

Radiation‐induced xerostomia in patients with head and neck cancer: a literature review

P Dirix, S Nuyts… - … International Journal of …, 2006 - Wiley Online Library
A dry mouth or xerostomia is one of the most common complications during and after
radiotherapy for head and neck cancer, because irreparable damage is caused to the …

A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the …

G Peng, T Wang, K Yang, S Zhang, T Zhang… - Radiotherapy and …, 2012 - Elsevier
BACKGROUND AND PURPOSE: To compare clinical outcomes and toxicities of two-
dimensional conventional radiation therapy (2D-CRT) and intensity modulated radiation …

Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial

CM Nutting, JP Morden, KJ Harrington… - The lancet …, 2011 - thelancet.com
Background Xerostomia is the most common late side-effect of radiotherapy to the head and
neck. Compared with conventional radiotherapy, intensity-modulated radiotherapy (IMRT) …

Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a …

EHN Pow, DLW Kwong, AS McMillan… - International Journal of …, 2006 - Elsevier
Purpose: To compare directly the effect of intensity-modulated radiotherapy (IMRT) vs.
conventional radiotherapy (CRT) on salivary flow and quality of life (QoL) in patients with …

Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies

L Veldeman, I Madani, F Hulstaert… - The lancet …, 2008 - thelancet.com
Since its introduction more than a decade ago, intensity-modulated radiotherapy (IMRT) has
spread to most radiotherapy departments worldwide for a wide range of indications. The …

Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a …

MR Vergeer, PAH Doornaert, DHF Rietveld… - International Journal of …, 2009 - Elsevier
PURPOSE: The purpose of this study was to compare intensity-modulated radiation therapy
(IMRT) and three-dimensional conventional radiotherapy (3D-CRT) with regard to patient …

A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: management strategies and economic impact

SB Jensen, AML Pedersen, A Vissink… - Supportive care in …, 2010 - Springer
Purpose This systematic review aimed to assess the literature for management strategies
and economic impact of salivary gland hypofunction and xerostomia induced by cancer …

A review of the clinical evidence for intensity-modulated radiotherapy

J Staffurth - Clinical oncology, 2010 - Elsevier
AIMS: Intensity-modulated radiotherapy (IMRT) is a development of three-dimensional
conformal radiotherapy that offers improvements in dosimetry in many clinical scenarios …

[HTML][HTML] Quality-of-life among head and neck cancer survivors at one year after treatment–a systematic review

WKW So, RJ Chan, DNS Chan, BGM Hughes… - European journal of …, 2012 - Elsevier
BACKGROUND: The importance of quality-of-life (QoL) research has been recognised over
the past two decades in patients with head and neck (H&N) cancer. The aims of this …