Melanin is one of the most abundant pigments found in the biosphere. Owing to its high
biocompatibility and diverse biological activities, it has been widely applied as a functional …

Objectives The co-occurrence of melanoma and Parkinson's disease (PD) is higher than
expected. We review the relationship between melanoma and PD, then proffer a hypothesis …

Melanoma arising from pigment-producing melanocytes is the deadliest form of skin cancer.
Extensive ultraviolet light exposure is a major cause of melanoma and individuals with low …

Melanoma is an extremely aggressive form of skin cancer that can spread to the lungs,
brain, and liver, among other vital organs. Melanoma cells, unlike any other cancer cells …

Despite novel therapy regimens and extensive research, chemoresistance remains a
challenge in leukemia treatment. Of note, recent studies revealed lysosomes as regulators of …

Two-pore channels TPC1 and TPC2 are ubiquitously expressed pathophysiologically
relevant proteins that reside on endolysosomal vesicles. Here, we review the …

Melanoma is an aggressive form of skin cancer with a high prevalence in the population. An
early diagnosis is crucial to cure this disease. Still, when this is not possible, combining …

ABSTRACT When Salmonella Typhimurium is ingested by German cockroaches, the
bacteria replicate in the gut and persist for at least 7 d, enabling transmission in the feces …

Ca 2+ signalling is of prime importance in controlling numerous cell functions in the brain.
Endolysosomes are acidic organelles currently emerging as important Ca 2+ stores in …

The brown macroalgae Sargassum has been reported for its anti-UV and photoprotective
potential for industrial applications. This study evaluated the melanin inhibition activity of …