Bioactive compounds and biomedical applications of endophytic fungi: a recent review

AH Hashem, MS Attia, EK Kandil, MM Fawzi… - Microbial Cell …, 2023 - Springer
Human life has been significantly impacted by the creation and spread of novel species of
antibiotic-resistant bacteria and virus strains that are difficult to manage. Scientists and …

Exploring the phytochemicals and anti-cancer potential of the members of Fabaceae family: A comprehensive review

M Usman, WR Khan, N Yousaf, S Akram, G Murtaza… - Molecules, 2022 - mdpi.com
Cancer is the second-ranked disease and a cause of death for millions of people around the
world despite many kinds of available treatments. Phytochemicals are considered a vital …

[HTML][HTML] Genkwanin: An emerging natural compound with multifaceted pharmacological effects

N El Menyiy, S Aboulaghras, S Bakrim… - Biomedicine & …, 2023 - Elsevier
Plant bioactive molecules could play key preventive and therapeutic roles in chronological
aging and the pathogenesis of many chronic diseases, often accompanied by increased …

[HTML][HTML] Proximate composition and health benefit of Roselle leaf (Hibiscus sabdariffa). Insight on food and health benefits

GI Edo, PO Samuel, AN Jikah, GO Oloni… - Food Chemistry …, 2023 - Elsevier
Zobo leaves, also known as Roselle leaves are leaves of the Malvaceae plant Hibiscus
sabdariffa, they are a common culinary ingredient as well as a traditional medicine in many …

Recent advances in flavonoid-based nanocarriers as an emerging drug delivery approach for cancer chemotherapy

S Dewanjee, P Chakraborty, H Bhattacharya… - Drug Discovery …, 2023 - Elsevier
Highlights•Flavonoids exhibit therapeutic potential against different types of cancer
cells.•Poor pharmacokinetics and biopharmaceutical traits limit their therapeutic …

Apigetrin promotes TNFα-induced apoptosis, necroptosis, G2/M phase cell cycle arrest, and ROS generation through inhibition of NF-κB pathway in Hep3B liver …

PB Bhosale, A Abusaliya, HH Kim, SE Ha, MY Park… - Cells, 2022 - mdpi.com
Apigetrin (7-(β-D-glucopyranosyloxy)-4′, 5-dihydroxyflavone), a glycoside bioactive dietary
flavonoid derived from Taraxacum officinale and Teucrium gnaphalodes, is known to …

Polyphenols and their nanoformulations: Protective effects against human diseases

S Anand, R Sowbhagya, MA Ansari, MA Alzohairy… - Life, 2022 - mdpi.com
Polyphenols are the secondary metabolites synthesized by the plants as a part of defense
machinery. Owing to their antioxidant, anti-inflammatory, anticancerous, antineoplastic, and …

Bacterial Endophytes from Moringa oleifera Leaves as a Promising Source for Bioactive Compounds

AH Hashem, AA Al-Askar, H Abd Elgawad… - Separations, 2023 - mdpi.com
Bacterial endophytes reside within the tissues of living plant species without causing any
harm or disease to their hosts. Bacterial endophytes have produced a variety of bioactive …

A decennary update on diverse heterocycles and their intermediates as privileged scaffolds for cathepsin B inhibition

B Saroha, G Kumar, M Kumari, R Kaur… - International Journal of …, 2022 - Elsevier
The identification of x-ray crystal structure of cathepsin B (CTSB) in the early 90's enabled
researchers to embark on a journey to understand and demystify its multiple catalytic …

Why Do Dietary Flavonoids Have a Promising Effect as Enhancers of Anthracyclines? Hydroxyl Substituents, Bioavailability and Biological Activity

A Golonko, AJ Olichwier, R Swislocka… - International Journal of …, 2022 - mdpi.com
Anthracyclines currently play a key role in the treatment of many cancers, but the limiting
factor of their use is the widespread phenomenon of drug resistance and untargeted toxicity …