Osteoarthritis (OA) is a disabling condition that affects billions of people worldwide and
places a considerable burden on patients and on society owing to its prevalence and …

Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …

Osteoarthritis (OA) is an age-related disease, characterized by cartilage degeneration. The
pathogenesis of OA is complicated and the current therapeutic approaches for OA are …

Biomechanical studies are expanding across a variety of fields, from biomedicine to
biomedical engineering. From the molecular to the system level, mechanical stimuli are …

Purpose To evaluate the mid-and long-term efficacy of autologous chondrocyte implantation
(ACI) and matrix-assisted chondrocyte implantation (MACI) to treat patients with knee …

Articular cartilage is a complex connective tissue with the fundamental functions of load
bearing, shock absorption and lubrication in joints. However, traumatic events, aging and …

The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed
significant challenges for healthcare practitioners, researchers, and individuals suffering …

Articular cartilage (AC) is the thin tissue that covers the long bone ends in the joints and that
ensures the transmission of forces between adjacent bones while allowing nearly …

For a long time, PLS3 (plastin 3, also known as T-plastin or fimbrin) has been considered a
rather inconspicuous protein, involved in F-actin-binding and-bundling. However, in recent …