Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Increased life expectancy is posing unprecedented challenges to healthcare systems
worldwide. These include a sharp increase in the prevalence of chronic kidney disease …

Periodontitis and chronic kidney disease are chronic conditions with high community
prevalence across the world. Patients with chronic kidney disease have been noted to have …

Within the past several decades, the emergence of new viral diseases with severe health
complications and mortality is evidence of an age-dependent, compromised bodily response …

Immunosenescence involves a series of ageing-induced alterations in the immune system
and is characterized by two opposing hallmarks: defective immune responses and …

Background: Chronic kidney disease of non-traditional origin (CKDnt) is common among
Mesoamerican sugarcane workers. Recurrent heat stress and dehydration is a leading …

Chronic kidney disease (CKD) is one of the major health problems of the modern age. It
represents an important public health challenge with an ever-lasting rising prevalence …

Background Systemic inflammation has been linked to diseases and frailty. However, little is
known about the effect of systemic inflammation on frailty progression with a longitudinal …

Aging as an inevitable phenomenon is associated with pervasive changes in physiological
functions. There is a relationship between aging and the increase of several chronic …

Aging is characterized by several progressive physiological changes, including changes in
the circadian rhythm. Circadian rhythms influence behavior, physiology, and metabolic …