A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

Mounting evidence indicates that microglia, which are the resident immune cells of the brain,
play critical roles in a diverse array of neurodevelopmental processes required for proper …

Integration of sensory and molecular inputs from the environment shapes animal behaviour.
A major site of exposure to environmental molecules is the gastrointestinal tract, in which …

Numerous studies have emphasised the importance of the gut microbiota during early life
and its role in modulating neurodevelopment and behaviour. Epidemiological studies have …

Autism spectrum disorder (ASD) is defined by hallmark behaviors involving reduced
communication and social interaction as well as repetitive activities and restricted interests …

Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and
entrain each other, and thus affect host health and immune-mediated diseases. Here, we …

Autism spectrum disorders (ASD) are serious, highly variable neurodevelopmental
disorders, commonly characterized by the manifestation of specific behavioral abnormalities …

Mounting evidence suggests a link between gut microbiota abnormalities and post-traumatic
stress disorder (PTSD). However, whether and how the gut microbiota influences PTSD …

Uremic encephalopathy encompasses a wide range of central nervous system
abnormalities associated with poor kidney function occurring with either progressive chronic …

Acute kidney injury (AKI) occurs in about half of critically ill patients and is associated with
high in-hospital mortality, increased long-term mortality postdischarge, and subsequent …