[HTML][HTML] Flavoprotein monooxygenases: versatile biocatalysts

CE Paul, D Eggerichs, AH Westphal, D Tischler… - Biotechnology …, 2021 - Elsevier
Flavoprotein monooxygenases (FPMOs) are single-or two-component enzymes that
catalyze a diverse set of chemo-, regio-and enantioselective oxyfunctionalization reactions …

Flavin dependent monooxygenases

MME Huijbers, S Montersino, AH Westphal… - Archives of biochemistry …, 2014 - Elsevier
Flavin-dependent monooxygenases catalyze a wide variety of chemo-, regio-and
enantioselective oxygenation reactions. As such, they are involved in key biological …

Baeyer–Villiger monooxygenases: tunable oxidative biocatalysts

MJLJ Fürst, A Gran-Scheuch, FS Aalbers… - ACS …, 2019 - ACS Publications
Pollution, accidents, and misinformation have earned the pharmaceutical and chemical
industry a poor public reputation, despite their undisputable importance to society …

Baeyer–Villiger monooxygenases: recent advances and future challenges

DET Pazmiño, HM Dudek, MW Fraaije - Current opinion in chemical …, 2010 - Elsevier
Baeyer–Villiger monooxygenases For many enzyme classes, a wealth of information on, for
example, structure and mechanism has been generated in the last few decades. While the …

[HTML][HTML] Chopping and changing: the evolution of the flavin-dependent monooxygenases

ML Mascotti, MJ Ayub, N Furnham, JM Thornton… - Journal of molecular …, 2016 - Elsevier
Flavin-dependent monooxygenases play a variety of key physiological roles and are also
very powerful biotechnological tools. These enzymes have been classified into eight …

Hot spots for the protein engineering of Baeyer-Villiger monooxygenases

K Balke, A Beier, UT Bornscheuer - Biotechnology advances, 2018 - Elsevier
Abstract Baeyer-Villiger monooxygenases (BVMOs) are versatile biocatalysts for the
conversion of ketones to lactones or esters while also being able to efficiently oxidize …

A Baeyer-Villiger monooxygenase from Cupriavidus basilensis catalyzes asymmetric synthesis of (R)-lansoprazole and other pharmaco-sulfoxides

F Liu, C Shou, Q Geng, C Zhao, J Xu, H Yu - Applied Microbiology and …, 2021 - Springer
Biocatalytic synthesis of pharmaco-chiral sulfoxides has gained interest in recent years for
its environmental friendliness. However, only a few natural biocatalysts can be used for the …

Native roles of Baeyer–Villiger monooxygenases in the microbial metabolism of natural compounds

C Tolmie, MS Smit, DJ Opperman - Natural product reports, 2019 - pubs.rsc.org
Covering: up to end of June 2018 Baeyer–Villiger monooxygenases (BVMOs) are flavin-
dependent enzymes that catalyse the oxidation of ketones and cyclic ketones to esters and …

[HTML][HTML] Rhodococcus as a Versatile Biocatalyst in Organic Synthesis

H Busch, PL Hagedoorn, U Hanefeld - International journal of molecular …, 2019 - mdpi.com
The application of purified enzymes as well as whole-cell biocatalysts in synthetic organic
chemistry is becoming more and more popular, and both academia and industry are keen …

Switch in cofactor specificity of a Baeyer–Villiger monooxygenase

A Beier, S Bordewick, M Genz, S Schmidt… - …, 2016 - Wiley Online Library
Abstract Baeyer–Villiger monooxygenases (BVMOs) catalyze the oxidation of ketones to
esters or lactones by using molecular oxygen and a cofactor. Type I BVMOs display a strong …