Opioid overdose: limitations in naloxone reversal of respiratory depression and prevention of cardiac arrest

M van Lemmen, J Florian, Z Li, M van Velzen… - …, 2023 - ingentaconnect.com
Opioids are effective analgesics, but they can have harmful adverse effects, such as
addiction and potentially fatal respiratory depression. Naloxone is currently the only …

Electrochemical sensors for the detection of fentanyl and its analogs: Foundations and recent advances

MW Glasscott, KJ Vannoy, PUAI Fernando… - TrAC Trends in …, 2020 - Elsevier
The opioid crisis has proliferated at an unprecedented rate worldwide, posing significant
public health challenges. This review presents the current state of electrochemical methods …

Carfentanil–from an animal anesthetic to a deadly illicit drug

JB Zawilska, K Kuczyńska, W Kosmal… - Forensic science …, 2021 - Elsevier
The use of novel synthetic opioids as recreational drugs has become a public health
concern as they are implicated in numerous fatal intoxications across the world. Synthetic …

Carfentanil: a narrative review of its pharmacology and public health concerns

JLS Leen, DN Juurlink - Canadian Journal of Anesthesia, 2019 - search.proquest.com
Carfentanil is a synthetic fentanyl analogue approved for veterinary use. It is a mu-opioid
receptor agonist with an estimated analgesic potency approximately 10,000 times that of …

[图书][B] Novel psychoactive substances: classification, pharmacology and toxicology

PI Dargan, DM Wood - 2021 - books.google.com
Novel Psychoactive Substances: Classification, Pharmacology and Toxicology, Second
Edition provides readers with a comprehensive examination on the classification, detection …

Leveraging body-worn camera footage to better understand opioid overdoses and the impact of police-administered naloxone

MD White, S Watts, C Orosco… - American journal of …, 2022 - ajph.aphapublications.org
Objectives. To investigate what transpires at opioid overdoses where police administer
naloxone and to identify the frequency with which concerns about police-administered …

Perceived vulnerability to overdose-related arrests among people who use drugs in Maryland

S Rouhani, KE Schneider, A Rao, GJ Urquhart… - International journal of …, 2021 - Elsevier
Background People who use drugs (PWUD) must weigh complex legal scenarios when
seeking help during overdose events. Good Samaritan laws (GSL) offer limited immunity for …

[HTML][HTML] Evaluation of fentanyl immunoassay test strips for rapid in-situ detection of fentanyl and fentanyl analogs in seized samples and alternative matrices

C Norman, V Marland, C McKenzie, H Ménard… - International Journal of …, 2023 - Elsevier
Background Ion mobility spectrometry is used for the rapid detection of drugs at points of
security but are unable to differentiate some drugs leading to the instrument alarming for a …

Narcan and Narcan't: Implementation factors influencing police officer use of Narcan

L Berardi, S Bucerius, KD Haggerty, H Krahn - Social science & medicine, 2021 - Elsevier
First responders—including police officers—play a prominent role in managing the risk of
fentanyl overdoses. In many jurisdictions, they have Naloxone (also commercially available …

“You can see those concentric rings going out”: emergency personnel's experiences treating overdose and perspectives on policy-level responses to the opioid crisis …

E Saunders, SA Metcalf, O Walsh, SK Moore… - Drug and alcohol …, 2019 - Elsevier
Background In parallel to a substantial increase in opioid overdose deaths in New
Hampshire (NH), emergency personnel experienced an increase in opioid-related …