D-Aspartic acid: an endogenous amino acid with an important neuroendocrine role

A D'Aniello - Brain research reviews, 2007 - Elsevier
d-Aspartic acid (d-Asp), an endogenous amino acid present in vertebrates and
invertebrates, plays an important role in the neuroendocrine system, as well as in the …

d‐Amino acids in biological systems

S Du, M Wey, DW Armstrong - Chirality, 2023 - Wiley Online Library
Investigations on the occurrence and biochemical roles of free D‐amino acids and D‐amino
acid‐containing peptides and proteins in living systems have increased in frequency and …

Occurrence of D‐aspartic acid and N‐methyl‐D‐aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth …

AD‧ Aniello, MM Di Fiore, GH Fisher… - The FASEB …, 2000 - Wiley Online Library
Using two specific and sensitive fluorometric/HPLC methods and a GC‐MS method, alone
and in combination with D‐aspartate oxidase, we have demonstrated for the first time that N …

[HTML][HTML] D-Aspartate stimulation of testosterone synthesis in rat Leydig cells

Y Nagata, H Homma, JA Lee, K Imai - FEBS letters, 1999 - Elsevier
d-Aspartate increases human chorionic gonadotropin-induced testosterone production in
purified rat Leydig cells. l-Aspartate, d-, l-glutamate or d-, l-asparagine could not substitute …

d-Aspartate acts as a signaling molecule in nervous and neuroendocrine systems

N Ota, T Shi, JV Sweedler - Amino acids, 2012 - Springer
Abstract d-Aspartate (d-Asp) is an endogenous amino acid in the central nervous and
reproductive systems of vertebrates and invertebrates. High concentrations of d-Asp are …

The Role of d-Aspartic Acid and N-Methyl-d-Aspartic Acid in the Regulation of Prolactin Release

G D'Aniello, A Tolino, A D'aniello, F Errico… - …, 2000 - academic.oup.com
In this study, using an enzymatic HPLC method in combination with d-aspartate oxidase, we
show that N-methyl-d-aspartate (NMDA) is present at nanomolar levels in rat nervous …

Improvement of post-thawed sperm quality and fertility of Arian rooster by oral administration of d-aspartic acid

M Ansari, M Zhandi, H Kohram, M Zaghari, M Sadeghi… - Theriogenology, 2017 - Elsevier
This study was conducted to investigate the effect of d-Aspartic acid (D-Asp) on post-thawed
sperm quality, fertility and hatchability outcomes in male broiler breeders. Twenty 55-week …

Current knowledge of d-aspartate in glandular tissues

MM Di Fiore, A Santillo, G Chieffi Baccari - Amino Acids, 2014 - Springer
Free d-aspartate (d-Asp) occurs in substantial amounts in glandular tissues. This paper
reviews the existing work on d-Asp in vertebrate exocrine and endocrine glands, with …

[HTML][HTML] Occurrence of D-aspartic acid in human seminal plasma and spermatozoa: possible role in reproduction

G D'Aniello, S Ronsini, F Guida, P Spinelli… - Fertility and sterility, 2005 - Elsevier
OBJECTIVE: To determine D-aspartic acid (D-Asp) in human seminal plasma and
spermatozoa in fertile and infertile donors. DESIGN: Prospective observation study …

[HTML][HTML] The putative effects of D-Aspartic acid on blood testosterone levels: A systematic review

F Roshanzamir, SM Safavi - International journal of reproductive …, 2017 - ncbi.nlm.nih.gov
Background: D-Aspartic acid (D-Asp) is in invertebrate and vertebrate neuroendocrine
tissues, where it carries out important physiological functions. Recently, it has been reported …