[HTML][HTML] Use of HIV recency assays for HIV incidence estimation and other surveillance use cases: systematic review

SN Facente, E Grebe, AD Maher, D Fox… - JMIR public health …, 2022 - publichealth.jmir.org
Background: HIV assays designed to detect recent infection, also known as “recency
assays,” are often used to estimate HIV incidence in a specific country, region, or …

Recent HIV Infection: Diagnosis and Public Health Implications

GK Nikolopoulos, AG Tsantes - Diagnostics, 2022 - mdpi.com
The early period of infection with human immunodeficiency virus (HIV) has been associated
with higher infectiousness and, consequently, with more transmission events. Over the last …

Detection of recent HIV-1 infection using a new limiting-antigen avidity assay: potential for HIV-1 incidence estimates and avidity maturation studies

YT Duong, M Qiu, AK De, K Jackson, T Dobbs, AA Kim… - PloS one, 2012 - journals.plos.org
Background Accurate and reliable laboratory methods are needed for estimation of HIV-1
incidence to identify the high-risk populations and target and monitor prevention efforts. We …

Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes

YT Duong, R Kassanjee, A Welte, M Morgan, A De… - PloS one, 2015 - journals.plos.org
Background Mean duration of recent infection (MDRI) and misclassification of long-term HIV-
1 infections, as proportion false recent (PFR), are critical parameters for laboratory-based …

Timing and order of transmission events is not directly reflected in a pathogen phylogeny

E Romero-Severson, H Skar, I Bulla… - Molecular biology …, 2014 - academic.oup.com
Pathogen phylogenies are often used to infer spread among hosts. There is, however, not
an exact match between the pathogen phylogeny and the host transmission history. Here …

HIV incidence determination in the United States: a multiassay approach

O Laeyendecker, R Brookmeyer… - The Journal of …, 2013 - academic.oup.com
Background. Accurate testing algorithms are needed for estimating human
immunodeficiency virus (HIV) incidence from cross-sectional surveys. Methods. We …

Facilitating next‐generation pre‐exposure prophylaxis clinical trials using HIV recent infection assays: a consensus statement from the Forum HIV Prevention Trial …

N Parkin, F Gao, E Grebe, A Cutrell… - Clinical …, 2023 - Wiley Online Library
Standard‐of‐care HIV pre‐exposure prophylaxis (PrEP) is highly efficacious, but uptake of
and persistence on a daily oral pill is low in many settings. Evaluation of alternate PrEP …

Estimation of HIV incidence using multiple biomarkers

R Brookmeyer, J Konikoff… - American journal of …, 2013 - academic.oup.com
The incidence of human immunodeficiency virus (HIV) is the rate at which new HIV
infections occur in populations. The development of accurate, practical, and cost-effective …

Performance of a limiting-antigen avidity enzyme immunoassay for cross-sectional estimation of HIV incidence in the United States

J Konikoff, R Brookmeyer, AF Longosz, MM Cousins… - PloS one, 2013 - journals.plos.org
Background A limiting antigen avidity enzyme immunoassay (HIV-1 LAg-Avidity assay) was
recently developed for cross-sectional HIV incidence estimation. We evaluated the …

Evaluation of sequence ambiguities of the HIV-1 pol gene as a method to identify recent HIV-1 infection in transmitted drug resistance surveys

E Andersson, W Shao, I Bontell, F Cham… - Infection, Genetics and …, 2013 - Elsevier
Identification of recent HIV infection within populations is a public health priority for accurate
estimation of HIV incidence rates and transmitted drug resistance at population level …