The real-time, dynamic optical visualization of lesions and margins ensures not only
complete resection of the malignant tissues but also better preservation of the vital …

Synthetic progestogens (progestins) have been linked to increased breast cancer risk;
however, the role of endogenous progesterone in breast physiology and carcinogenesis is …

Glutathione (GSH) mediates a wide variety of biological events and human diseases.
Although it has been the subject of intense study in recent years, a further understanding of …

Glutathione plays many important roles in biological processes; however, the dynamic
changes of glutathione concentrations in living cells remain largely unknown. Here, we …

Ruthenium (II) polypyridine complexes are one of the most extensively studied and
developed systems in the family of luminescent transition-metal complexes. Notably, there …

Emerging evidence suggests that cancer is populated and maintained by tumour-initiating
cells (TICs) with stem-like properties similar to those of adult tissue stem cells. Despite …

Breast cancer risk for carriers of BRCA1 pathological variants is modified by genetic factors.
Genetic variation in HMMR may contribute to this effect. However, the impact of risk …

We published the first paper to characterize GPX2 (aka GSHPx-GI) as a selenoenzyme with
glutathione peroxidase activity in 1993. Among the four Se-GPX isozymes, GPX1-4, GPX1 …

Breast cancer prevention is daunting, yet not an unsurmountable goal. Mammary stem and
progenitors have been proposed as the cells‐of‐origin in breast cancer. Here, we present …

Photodynamic therapy (PDT) is a prominent strategy in contemporary oncology for its
potential to selectively eradicate cancer cells. However, the non-specific accumulation of …