The ICSI procedure from past to future: a systematic review of the more controversial aspects

P Rubino, P Viganò, A Luddi… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND ICSI is currently the most commonly used assisted reproductive technology,
accounting for 70–80% of the cycles performed. This extensive use, even excessive, is partly …

Gamete activation: basic knowledge and clinical applications

E Tosti, Y Ménézo - Human Reproduction Update, 2016 - academic.oup.com
Background The first clues to the process of gamete activation date back to nearly 60 years
ago. The mutual activation of gametes is a crucial event during fertilization. In the testis and …

[HTML][HTML] Does the use of calcium ionophore during artificial oocyte activation demonstrate an effect on pregnancy rate? A meta-analysis

S Murugesu, S Saso, BP Jones, T Bracewell-Milnes… - Fertility and sterility, 2017 - Elsevier
Objective To study the effect, if any, of calcium ionophore as a method of artificial oocyte
activation (AOA) on pregnancy outcomes and fertilization rates. Design Meta-analysis of …

[HTML][HTML] Application of a ready-to-use calcium ionophore increases rates of fertilization and pregnancy in severe male factor infertility

T Ebner, M Köster, O Shebl, M Moser, H Van der Ven… - Fertility and sterility, 2012 - Elsevier
OBJECTIVE: To analyze whether a ready-to-use calcium ionophore improves outcomes,
from fertilization to live birth, in patients with severe male factor infertility. DESIGN: Artificial …

Treatment with Ca2+ ionophore improves embryo development and outcome in cases with previous developmental problems: a prospective multicenter study

T Ebner, P Oppelt, M Wöber, P Staples… - Human …, 2015 - academic.oup.com
STUDY QUESTION Does calcium ionophore treatment (A23187, calcimycin) improve
embryo development and outcome in patients with a history of developmental …

Pregnancy and neonatal outcomes of artificial oocyte activation in patients undergoing frozen–thawed embryo transfer: A 6-year population-based retrospective study

B Li, Y Zhou, Z Yan, M Li, S Xue, R Cai, Y Fu… - Archives of gynecology …, 2019 - Springer
Purpose To evaluate the impact of artificial oocyte activation (AOA) in pregnancy and
neonatal outcomes in infertile patients undergoing cryopreserved embryo transfer. Method …

Analysis of clinical outcomes with respect to spermatozoan origin after artificial oocyte activation with a calcium ionophore

HJ Yoon, IH Bae, HJ Kim, JM Jang, YS Hur… - Journal of assisted …, 2013 - Springer
Purpose Fertilization failures have occurred repeatedly in reproductive centers after
intracytoplasmic sperm injection (ICSI) and artificial oocyte activation (AOA) has been used …

[HTML][HTML] Effects of selenium, calcium and calcium ionophore on human oocytes in vitro maturation in a chemically defined medium

M Makki, E Saboori, MA Sabbaghi, R Aram… - Iranian journal of …, 2012 - ncbi.nlm.nih.gov
Background: In vitro maturation (IVM) of human oocytes is an emerging procedure quickly
incorporated into the world of assisted reproductive technologies. As an effective method of …

[HTML][HTML] Treatment with Calcium Ionophore Improves The Results in Patients with Previous Unsuccessful Attempts at The Fertilization: A Cohort Study

A Tejera, LA Ferri, PG Izquierdo… - … Journal of Fertility & …, 2021 - ncbi.nlm.nih.gov
Background: The objective of this study is to evaluate artificial oocyte activation (AOA) with
calcium ionophore (CaI) in a subsequent attempt at fertilisation in patients after extremely …

Наступление беременности и роды у пациенток после коррекции расположения пронуклеусов в ооцитах с использованием ионофора кальция

МП Яхьярова, ИА Заставский, АВ Ким - Репродуктивная медицина, 2022 - repromed.kz
Аннотация Актуальность: Непрерывное совершенствование методов вспомогательных
репродуктивных технологий (ВРТ) помогает преодолеть практически все виды …