We will soon have complete genome sequences from thousands of species, as well as from many individuals within species. This coming explosion of information will transform our …
The past few years have witnessed a revolution in our ability to obtain DNA from ancient humans. This important new data has added to our knowledge from archaeology and …
We assembled genome-wide data from 16 prehistoric Africans. We show that the anciently divergent lineage that comprises the primary ancestry of the southern African San had a …
As modern humans migrated out of Africa, they encountered many new environmental conditions, including greater temperature extremes, different pathogens and higher …
Genetic studies have consistently indicated a single common origin of Native American groups from Central and South America,,,. However, some morphological studies have …
Abstract The 1000 Genomes Project aims to provide a deep characterisation of human genome sequence variation as a foundation for investigating the relationship between …
EK Karlsson, DP Kwiatkowski, PC Sabeti - Nature Reviews Genetics, 2014 - nature.com
The ancient biological'arms race'between microbial pathogens and humans has shaped genetic variation in modern populations, and this has important implications for the growing …
Organisms can often adapt surprisingly quickly to evolutionary challenges, such as the application of pesticides or antibiotics, suggesting an abundant supply of adaptive genetic …
Comparing allele frequencies among populations that differ in environment has long been a tool for detecting loci involved in local adaptation. However, such analyses are complicated …