Harnessing genomics for delineating conservation units

WC Funk, JK McKay, PA Hohenlohe… - Trends in ecology & …, 2012 - cell.com
Genomic data have the potential to revolutionize the delineation of conservation units (CUs)
by allowing the detection of adaptive genetic variation, which is otherwise difficult for rare …

Genomics and the future of conservation genetics

FW Allendorf, PA Hohenlohe, G Luikart - Nature reviews genetics, 2010 - nature.com
We will soon have complete genome sequences from thousands of species, as well as from
many individuals within species. This coming explosion of information will transform our …

[图书][B] Who we are and how we got here: Ancient DNA and the new science of the human past

D Reich - 2018 - books.google.com
The past few years have witnessed a revolution in our ability to obtain DNA from ancient
humans. This important new data has added to our knowledge from archaeology and …

[HTML][HTML] Reconstructing prehistoric African population structure

P Skoglund, JC Thompson, ME Prendergast, A Mittnik… - Cell, 2017 - cell.com
We assembled genome-wide data from 16 prehistoric Africans. We show that the anciently
divergent lineage that comprises the primary ancestry of the southern African San had a …

Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA

E Huerta-Sánchez, X Jin, Asan, Z Bianba, BM Peter… - Nature, 2014 - nature.com
As modern humans migrated out of Africa, they encountered many new environmental
conditions, including greater temperature extremes, different pathogens and higher …

Genetic evidence for two founding populations of the Americas

P Skoglund, S Mallick, MC Bortolini, N Chennagiri… - Nature, 2015 - nature.com
Genetic studies have consistently indicated a single common origin of Native American
groups from Central and South America,,,. However, some morphological studies have …

[HTML][HTML] A map of human genome variation from population scale sequencing

1000 Genomes Project Consortium - Nature, 2010 - ncbi.nlm.nih.gov
Abstract The 1000 Genomes Project aims to provide a deep characterisation of human
genome sequence variation as a foundation for investigating the relationship between …

Natural selection and infectious disease in human populations

EK Karlsson, DP Kwiatkowski, PC Sabeti - Nature Reviews Genetics, 2014 - nature.com
The ancient biological'arms race'between microbial pathogens and humans has shaped
genetic variation in modern populations, and this has important implications for the growing …

Population genomics of rapid adaptation by soft selective sweeps

PW Messer, DA Petrov - Trends in ecology & evolution, 2013 - cell.com
Organisms can often adapt surprisingly quickly to evolutionary challenges, such as the
application of pesticides or antibiotics, suggesting an abundant supply of adaptive genetic …

Robust identification of local adaptation from allele frequencies

T Günther, G Coop - Genetics, 2013 - academic.oup.com
Comparing allele frequencies among populations that differ in environment has long been a
tool for detecting loci involved in local adaptation. However, such analyses are complicated …