Mycobacterium tuberculosis uses sophisticated secretion systems, named 6 kDa early
secretory antigenic target (ESAT6) protein family secretion (ESX) systems (also known as …

Bacterial capsules have evolved to be at the forefront of the cell envelope, making them an
essential element of bacterial biology. Efforts to understand the Mycobacterium tuberculosis …

Type VII secretion systems (T7SSs) have a key role in the secretion of effector proteins in
non-pathogenic mycobacteria and pathogenic mycobacteria such as Mycobacterium …

The human pathogen Mycobacterium tuberculosis typically causes lung disease but can
also disseminate to other tissues. We identified a M. tuberculosis (Mtb) outbreak presenting …

The ESX-5 type VII secretion system is a membrane-spanning protein complex key to the
virulence of mycobacterial pathogens. However, the overall architecture of the fully …

The PE and PPE proteins of Mycobacterium tuberculosis have been studied with great
interest since their discovery. Named after the conserved proline (P) and glutamic acid (E) …

Mycobacterium tuberculosis requires a large number of secreted and exported proteins for
its virulence, immune modulation and nutrient uptake. Most of these proteins are transported …

The genome of Mycobacterium tuberculosis, the bacterium responsible for the disease
tuberculosis, contains an unusual family of abundant antigens (PE/PPEs). To date, certain …

Introduction Neutrophil granulocytes predominate in the lungs of patients infected with
Mycobacterium tuberculosis (Mtb) in earlier stages of the disease. During infection …

Streptococcus gallolyticus subspecies gallolyticus (Sgg) has a strong clinical association
with colorectal cancer (CRC) and actively promotes the development of colon tumors …