Diabetic cardiomyopathy (DCM) mainly refers to myocardial metabolic dysfunction caused
by high glucose, and hyperglycemia is an independent risk factor for cardiac function in the …

The global burden of diabetes mellitus and its related complications are currently increasing.
Diabetes mellitus affects the heart through various mechanisms including microvascular …

Diabetes affects every organ in the body and cardiovascular disease accounts for two-thirds
of the mortality in the diabetic population. Diabetes-related heart disease occurs in the form …

Significance: Diabetic cardiomyopathy (DCM) is a frequent complication occurring even in
well-controlled asymptomatic diabetic patients, and it may advance to heart failure (HF) …

Background Cardiovascular diseases, including diabetic cardiomyopathy, are major causes
of death in people with type 2 diabetes. Aldose reductase activity is enhanced in …

Cardiovascular diseases account for approximately one third of all deaths globally. Obese
and diabetic patients have a high likelihood of dying from complications associated with …

Both heart failure with reduced ejection fraction (HFrEF) and with preserved ejection fraction
(HFpEF) are associated with high morbidity and mortality. Although many established …

Leptin is an adipokine that has been linked with the cardiovascular complications resulting
from obesity such as hypertension and heart disease. Obese patients have high levels of …

Aims Impaired myocardial energy homeostasis plays an import role in the pathophysiology
of heart failure with preserved ejection fraction (HFpEF). Left ventricular relaxation has a …

The development of a diabetic cardiomyopathy is a multifactorial process, and evidence is
accumulating that defects in intracellular free calcium concentration [Ca 2+] i or its …