The role of hepatokines in NAFLD

N Stefan, F Schick, AL Birkenfeld, HU Häring, MF White - Cell metabolism, 2023 - cell.com
Non-alcoholic fatty liver disease (NAFLD) is not only a consequence of insulin resistance,
but it is also an important cause of insulin resistance and major non-communicable diseases …

Updated mechanisms of MASLD pathogenesis

Y Li, P Yang, J Ye, Q Xu, J Wu, Y Wang - Lipids in Health and Disease, 2024 - Springer
Metabolic dysfunction-associated steatotic liver disease (MASLD) has garnered
considerable attention globally. Changing lifestyles, over-nutrition, and physical inactivity …

TSC22D4 interacts with Akt1 to regulate glucose metabolism

S Demir, G Wolff, A Wieder, A Maida, L Bühler… - Science …, 2022 - science.org
Maladaptive insulin signaling is a key feature in the pathogenesis of severe metabolic
disorders, including obesity and diabetes. Enhancing insulin sensitivity represents a major …

TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells

M Sakurai, P Weber, G Wolff, A Wieder… - Biochemical and …, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH) and liver
fibrosis emerge as progressive liver diseases that accompany metabolic syndrome usually …

Macroscopic label-free biomedical imaging with shortwave infrared Raman scattering

BA Arus, J Yiu, JGP Lingg, A Hofmann, AR Fumo, H Ji… - bioRxiv, 2024 - biorxiv.org
Shortwave infrared (SWIR) imaging provides enhanced tissue penetration and reduced
autofluorescence in clinical and pre-clinical applications. However, existing applications …

Recent Advances in Promoting Bone Regeneration in Type 2 Diabetes Using Drug Delivery Vehicles and Vehicle‐Free Therapeutics

Y Pesaran Afsharian, M Rahimnejad… - Advanced … - Wiley Online Library
The incidence of type 2 diabetes (T2DM) increases significantly worldwide. Due to
consistent hyperglycemia, insulin resistance, and chronic inflammation, T2DM patients …

Novel Molecular Mechanisms of TSC22D4 action in development of Diabetes Mellitus

S Demir - 2022 - archiv.ub.uni-heidelberg.de
The pathogenesis of Type 2 Diabetes (T2D) manifests itself with elevated blood glucose and
insulin levels. At the molecular level, dysregulations in the insulin signaling pathway cause …

TSC22D4 interacts with Akt1 in response metabolic and stress signals

S Demir, G Wolff, A Wieder, A Maida, M Rahm… - bioRxiv, 2021 - biorxiv.org
Abstract Transforming Growth Factor β 1 Stimulated Clone 22 D4 (TSC22D4) is an
intrinsically disordered protein that regulates cellular and physiological processes such as …