Regulation of bacterial virulence by Csr (Rsm) systems

CA Vakulskas, AH Potts, P Babitzke… - Microbiology and …, 2015 - Am Soc Microbiol
Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …

Specificity and nonspecificity in RNA–protein interactions

E Jankowsky, ME Harris - Nature reviews Molecular cell biology, 2015 - nature.com
To fully understand the regulation of gene expression, it is critical to quantitatively define
whether and how RNA-binding proteins (RBPs) discriminate between alternative binding …

Global RNA recognition patterns of post‐transcriptional regulators Hfq and CsrA revealed by UV crosslinking in vivo

E Holmqvist, PR Wright, L Li, T Bischler… - The EMBO …, 2016 - embopress.org
The molecular roles of many RNA‐binding proteins in bacterial post‐transcriptional gene
regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA …

Global regulation by CsrA and its RNA antagonists

T Romeo, P Babitzke - Microbiology spectrum, 2018 - Am Soc Microbiol
The sequence-specific RNA binding protein CsrA is employed by diverse bacteria in the
posttranscriptional regulation of gene expression. Its binding interactions with RNA have …

Structural basis of the non-coding RNA RsmZ acting as a protein sponge

O Duss, E Michel, M Yulikov, M Schubert, G Jeschke… - Nature, 2014 - nature.com
MicroRNA and protein sequestration by non-coding RNAs (ncRNAs) has recently generated
much interest. In the bacterial Csr/Rsm system, which is considered to be the most general …

Diverse mechanisms and circuitry for global regulation by the RNA-binding protein CsrA

C Pourciau, YJ Lai, M Gorelik, P Babitzke… - Frontiers in …, 2020 - frontiersin.org
The carbon storage regulator (Csr) or repressor of stationary phase metabolites (Rsm)
system of Gammaproteobacteria is among the most complex and best-studied …

RNA-binding proteins driving the regulatory activity of small non-coding RNAs in bacteria

AP Quendera, AF Seixas, RF Dos Santos… - Frontiers in molecular …, 2020 - frontiersin.org
Small non-coding RNAs (sRNAs) are critical post-transcriptional regulators of gene
expression. Distinct RNA-binding proteins (RBPs) influence the processing, stability and …

Small RNAs, 5′ UTR elements and RNA-binding proteins in intracellular bacteria: impact on metabolism and virulence

G Oliva, T Sahr, C Buchrieser - FEMS microbiology reviews, 2015 - academic.oup.com
Sequencing-based studies have illuminated increased transcriptional complexity within the
genome structure of bacteria and have resulted in the identification of many small regulatory …

Phloroglucinol Derivatives in Plant-Beneficial Pseudomonas spp.: Biosynthesis, Regulation, and Functions

A Biessy, M Filion - Metabolites, 2021 - mdpi.com
Plant-beneficial Pseudomonas spp. aggressively colonize the rhizosphere and produce
numerous secondary metabolites, such as 2, 4-diacetylphloroglucinol (DAPG). DAPG is a …

ProNAB: database for binding affinities of protein–nucleic acid complexes and their mutants

K Harini, A Srivastava, A Kulandaisamy… - Nucleic acids …, 2022 - academic.oup.com
Protein–nucleic acid interactions are involved in various biological processes such as gene
expression, replication, transcription, translation and packaging. The binding affinities of …