Physiology of normal esophageal motility
RK Goyal, A Chaudhury - Journal of clinical gastroenterology, 2008 - journals.lww.com
The esophagus consists of 2 different parts. In humans, the cervical esophagus is composed
of striated muscles and the thoracic esophagus is composed of phasic smooth muscles. The …
of striated muscles and the thoracic esophagus is composed of phasic smooth muscles. The …
Signaling for contraction and relaxation in smooth muscle of the gut
KS Murthy - Annu. Rev. Physiol., 2006 - annualreviews.org
▪ Abstract Phosphorylation of Ser19 on the 20-kDa regulatory light chain of myosin II
(MLC20) by Ca2+/calmodulin-dependent myosin light-chain kinase (MLCK) is essential for …
(MLC20) by Ca2+/calmodulin-dependent myosin light-chain kinase (MLCK) is essential for …
BDNF rescues aging-associated internal anal sphincter dysfunction
A Singh, S Rattan - American Journal of Physiology …, 2021 - journals.physiology.org
Aging can lead to rectoanal incontinence due to internal anal sphincter (IAS) dysfunction,
which is characterized by a decrease in IAS tone and contractility and an increase in …
which is characterized by a decrease in IAS tone and contractility and an increase in …
Comprehensive understanding of regulatory mechanisms, physiological models and key enzymes in microalgal cells based on various concentrations of CO2
Z Wang, J Cheng, Y Sun, D Jia, Y Tang, W Yang… - Chemical Engineering …, 2023 - Elsevier
Carbon fixation from industrial flue gas with high concentrations of carbon dioxide (CO 2)
requires a comprehensive and systematic understanding of the physiological influences of …
requires a comprehensive and systematic understanding of the physiological influences of …
[HTML][HTML] Mast cell effects on esophageal smooth muscle and their potential role in eosinophilic esophagitis and achalasia
M Nelson, X Zhang, Z Pan… - American Journal of …, 2021 - journals.physiology.org
Mast cells and eosinophils are the key effector cells of allergic disorders. Although most
studies on eosinophilic esophagitis (EoE), an allergic disorder of the esophagus, have …
studies on eosinophilic esophagitis (EoE), an allergic disorder of the esophagus, have …
Sphingosine-1-phosphate–dependent activation of p38 MAPK maintains elevated peripheral resistance in heart failure through increased myogenic vasoconstriction
J Hoefer, MA Azam, JTE Kroetsch, H Leong-Poi… - Circulation …, 2010 - Am Heart Assoc
Rationale: Mechanisms underlying vasomotor abnormalities and increased peripheral
resistance exacerbating heart failure (HF) are poorly understood. Objective: To explore the …
resistance exacerbating heart failure (HF) are poorly understood. Objective: To explore the …
Ca2+ signalling in interstitial cells of Cajal contributes to generation and maintenance of tone in mouse and monkey lower oesophageal sphincters
The lower oesophageal sphincter (LES) generates tone and prevents reflux of gastric
contents. LES smooth muscle cells (SMCs) are relatively depolarised, facilitating activation …
contents. LES smooth muscle cells (SMCs) are relatively depolarised, facilitating activation …
Role of rho kinase in the functional and dysfunctional tonic smooth muscles
MAF de Godoy, S Rattan - Trends in pharmacological sciences, 2011 - cell.com
Tonic smooth muscles play pivotal roles in the pathophysiology of debilitating diseases of
the gastrointestinal and cardiovascular systems. Tonic smooth muscles differ from phasic …
the gastrointestinal and cardiovascular systems. Tonic smooth muscles differ from phasic …
Diagnosis and treatment strategy of achalasia subtypes and esophagogastric junction outflow obstruction based on high-resolution manometry
E Ihara, K Muta, K Fukaura, K Nakamura - Digestion, 2017 - karger.com
Background: Based on Chicago Classification version 3.0, the disorders of esophagogastric
junction outflow obstruction (EGJOO) include achalasia (types I, II and III) and EGJOO …
junction outflow obstruction (EGJOO) include achalasia (types I, II and III) and EGJOO …
Myosin light chain kinase is necessary for tonic airway smooth muscle contraction
Different interacting signaling modules involving Ca 2+/calmodulin-dependent myosin light
chain kinase, Ca 2+-independent regulatory light chain phosphorylation, myosin …
chain kinase, Ca 2+-independent regulatory light chain phosphorylation, myosin …