Over the past years, basic findings in cancer research have revealed metabolic symbiosis
between different cell types to cope with high energy demands under limited nutrient …

Adipose tissue is recognized as an important organ with metabolic, regulatory, and plastic
roles. Adipose tissue-derived stem cells (ASCs) with self-renewal properties localize in the …

Background Predicting prognosis in patients from large-scale genomic data is a
fundamentally challenging problem in genomic medicine. However, the prognosis still …

In acute myeloid leukemia (AML), molecular heterogeneity across patients constitutes a
major challenge for prognosis and therapy. AML with NPM1 mutation is a distinct genetic …

Cancer stem cells (CSCs) exist in colon cancer and exhibit characteristics of stem cells
which are due to lineages of tissues where they arise. Epithelial to mesenchymal transition …

Adult neurogenesis is one of the most important mechanisms contributing to brain
development, learning, and memory. Alterations in neurogenesis underlie a wide spectrum …

Pulpal infection is one of the most common causes of dental emergency admission. Tooth
pain due to infection caused by gram-negative bacteria is the main manifestation of this sort …

Although advanced lipidomics technology facilitates quantitation of intracellular lipid
components, little is known about the regulation of lipid metabolism in cancer cells. Here, we …

Weight loss≥ 5 percent is sufficient to significantly reduce health risks for obese people;
therefore, development of novel weight loss compounds with reduced toxicity is urgently …

Research on GPR34, which was discovered in 1999 as an orphan G protein-coupled
receptor of the rhodopsin-like class, disclosed its physiologic relevance only piece by piece …