The Na+/I Symporter (NIS): Mechanism and Medical Impact

C Portulano, M Paroder-Belenitsky… - Endocrine …, 2014 - academic.oup.com
Abstract The Na+/I− symporter (NIS) is the plasma membrane glycoprotein that mediates
active I− transport in the thyroid and other tissues, such as salivary glands, stomach …

Cardiomyocyte regeneration

N Kawaguchi, T Nakanishi - Cells, 2013 - mdpi.com
The heart was initially believed to be a terminally differentiated organ; once the
cardiomyocytes died, no recovery could be made to replace the dead cells. However …

Positron emission tomography based in-vivo imaging of early phase stem cell retention after intramyocardial delivery in the mouse model

C Lang, S Lehner, A Todica, G Boening… - European journal of …, 2013 - Springer
Purpose To establish PET as a tool for in-vivo quantification and monitoring of
intramyocardially transplanted stem cells after labelling with FDG in mice with induced …

In-vivo comparison of the acute retention of stem cell derivatives and fibroblasts after intramyocardial transplantation in the mouse model

C Lang, S Lehner, A Todica, G Boening… - European journal of …, 2014 - Springer
Purpose Various strategies have been applied to increase the engraftment of an
intramyocardial cell transplant (Tx) to treat ischemic myocardium. Thereby, co-transplanted …

SPECT and PET to optimize cardiac stem cell therapy

AT Chan, MR Abraham - Journal of Nuclear Cardiology, 2012 - Elsevier
Coronary artery disease (CAD) is one of the leading causes of death despite significant
advances in biomedical research. Myocardial infarction results in myocyte death, destruction …

Cell shape and cardiosphere differentiation: a revelation by proteomic profiling

N Kawaguchi, M Machida, K Hatta… - Biochemistry …, 2013 - Wiley Online Library
Stem cells (embryonic stem cells, somatic stem cells such as neural stem cells, and cardiac
stem cells) and cancer cells are known to aggregate and form spheroid structures. This …

Noninvasive stem cell tracking

FM Bengel - Journal of Nuclear Cardiology, 2011 - Springer
Cardiac stem cell therapy has received an enormous amount of attention in recent years and
it has been considered a promising approach for repair of damaged myocardium. 1-4 …

Echocardiographic evaluation of the effects of stem cell therapy on perfusion and function in ischemic cardiomyopathy

Y Inaba, BP Davidson, S Kim, YN Liu… - Journal of the American …, 2014 - Elsevier
Background Small animal models of ischemic left ventricular (LV) dysfunction are important
for the preclinical optimization of stem cell therapy. The aim of this study was to test the …

Cardiospheres

RR Smith - Manual of Research Techniques in Cardiovascular …, 2014 - Wiley Online Library
Cardiospheres are multicellular clusters of cardiac stem cells, partially differentiated
progenitor cells, and supporting cell types. They can be derived from tissue obtained from …

Medical imaging for cardiac regeneration using resident cardiac stem cells

SH Choi, SY Yoo, SM Yoo, KB Lee… - Imaging in …, 2013 - search.proquest.com
Resident progenitor/cardiac stem cells (CSCs) are known to improve cardiac function
through differentiation into cardiomyocytes and vascular lineages. To evaluate the effects of …