Multiple sclerosis (MS) has long been regarded as a chronic inflammatory disease of the
white matter that leads to demyelination and eventually to neurodegeneration. In the past …

Oligodendrocytes (OLs) are the myelinating cells of the central nervous system (CNS) during
development and throughout adulthood. They result from a complex and well controlled …

The central nervous system, once thought to be a site of immunological privilege, has since
been found to harbour immunocompetent cells and to communicate with the peripheral …

Objectives To investigate if brain gamma-aminobutyric acid (GABA) levels in patients with
relapsing-remitting multiple sclerosis (RRMS) are abnormal compared with healthy controls …

Multiple sclerosis (MS) is a demyelinating disorder of the central nervous system. Disease
progression is variable and unpredictable, warranting the development of biomarkers of …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS). Although emerging evidence has shown that changes in …

Converging areas of research have implicated glutamate and γ-aminobutyric acid (GABA)
as key players in neuronal signalling and other central functions. Further research is …

There is growing evidence for dysfunctional glutamatergic excitation and/or gamma‐
aminobutyric acid (GABA) ergic inhibition in patients with multiple sclerosis (MS). Cognitive …

Background Multimodal research combining biomarkers of intracortical activity and cortical
damage could shed light on pathophysiological and adaptive neural processes related to …

Repetitive transcranial magnetic stimulation (rTMS) induces changes in expression of
proteins engaged in the activity of excitatory and inhibitory systems, restores these functions …