Key players in the immune response to biomaterial scaffolds for regenerative medicine

L Chung, DR Maestas Jr, F Housseau… - Advanced drug delivery …, 2017 - Elsevier
The compatibility of biomaterials is critical to their structural and biological function in
medical applications. The immune system is the first responder to tissue trauma and to a …

The cutaneous microbiome and wounds: new molecular targets to promote wound healing

TR Johnson, BI Gómez, MK McIntyre… - International journal of …, 2018 - mdpi.com
The ecological community of microorganisms in/on humans, termed the microbiome, is vital
for sustaining homeostasis. While culture-independent techniques have revealed the role of …

PI (18: 1/18: 1) is a SCD1-derived lipokine that limits stress signaling

M Thürmer, A Gollowitzer, H Pein, K Neukirch… - Nature …, 2022 - nature.com
Cytotoxic stress activates stress-activated kinases, initiates adaptive mechanisms, including
the unfolded protein response (UPR) and autophagy, and induces programmed cell death …

Identification of rare, transient post-mitotic cell states that are induced by injury and required for whole-body regeneration in Schmidtea mediterranea

BW Benham-Pyle, CE Brewster, AM Kent… - Nature cell …, 2021 - nature.com
Regeneration requires the coordination of stem cells, their progeny and distant differentiated
tissues. Here, we present a comprehensive atlas of whole-body regeneration in Schmidtea …

Colonizing microbiota is associated with clinical outcomes in diabetic wound healing

G Wang, Z Lin, Y Li, L Chen, SK Reddy, Z Hu… - Advanced drug delivery …, 2023 - Elsevier
With the development of society and the improvement of life quality, more than 500 million
people are affected by diabetes. More than 10% of people with diabetes will suffer from …

The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1

B Zhang, D Fu, Q Xu, X Cong, C Wu, X Zhong… - Nature …, 2018 - nature.com
The senescence-associated secretory phenotype (SASP) can be provoked by side effects of
therapeutic agents, fueling advanced complications including cancer resistance. However …

Li-doped bioactive ceramics: promising biomaterials for tissue engineering and regenerative medicine

AR Farmani, MA Salmeh, Z Golkar… - Journal of Functional …, 2022 - mdpi.com
Lithium (Li) is a metal with critical therapeutic properties ranging from the treatment of
bipolar depression to antibacterial, anticancer, antiviral and pro-regenerative effects. This …

Microplastics exposure causes oxidative stress and microbiota dysbiosis in planarian Dugesia japonica

Y Han, X Zhang, P Liu, S Xu, D Chen, JN Liu… - … Science and Pollution …, 2022 - Springer
Planarians are widely used as water quality indicator species to provide early warning of
harmful pollution in aquatic ecosystems. However, the impact of microplastics on freshwater …

The ecology of freshwater planarians

M Vila-Farré, JC Rink - Planarian regeneration: Methods and protocols, 2018 - Springer
Planarians are on the rise as a model system for regeneration and stem cell dynamics.
Almost in parallel the interest in planarian field biology has declined. Besides representing …

Mechanically resolved imaging of bacteria using expansion microscopy

Y Lim, AL Shiver, M Khariton, KM Lane, KM Ng… - PLoS …, 2019 - journals.plos.org
Imaging dense and diverse microbial communities has broad applications in basic
microbiology and medicine, but remains a grand challenge due to the fact that many species …