Resveratrol is a polyphenol with diverse pharmacological activities, but its clinical efficacy is
limited due to low solubility/permeability, light-induced isomerization, auto-oxidation, and …

Lactoferrin (LF) is a naturally present iron-binding globulin with the structural properties of
an N-lobe strongly positively charged terminus and a cage-like structure of nano self …

HER2-positive breast cancer brain metastasis (HER2+ BCBM) is a refractory malignancy
with a high recurrence rate and poor prognosis. The efficacies of conventional treatments …

Bispecific nanoparticles (NPs) are conjugated with two antibodies that enhance T cell
cytotoxicity by sequentially targeting CD3 and tumor-specific proteins. This interaction …

Glioblastoma (GBM) is a highly aggressive cancer that currently lacks effective treatments.
Pyroptosis has emerged as a promising therapeutic approach for cancer, but there is still a …

Nanomedicine is currently focused on the design and development of nanocarriers that
enhance drug delivery to the brain to address unmet clinical needs for treating …

Blood-brain barrier (BBB) serves as an essential interface between central nervous system
(CNS) and its periphery, allowing selective permeation of ions, gaseous molecules, and …

Central nervous system (CNS) disorders and diseases are expected to rise sharply in the
coming years, partly because of the world's aging population. Medicines for the treatment of …

Cerebral ischemia and reperfusion are related to various situations like injuries after various
traumas, oxidative stress, increased calcium ion, capillary hypoperfusion, microvascular …

Neurodegenerative diseases (NDs) such as Alzheimer's disease (AD) and Parkinson's
disease (PD) are an accelerating global health problem as life expectancy rises worldwide …