Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage
tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it …

Osteoarthritis (OA) is the most prevalent joint disease, but neither preventive measures nor
disease-modifying drugs are available and a continuing need exists for safe and effective …

Articular chondrocytes are often expanded in vitro and then used to assist in healing
articular cartilage defects. We investigated the extent of dedifferentiation in monolayer …

Articular cartilage damage is a persistent and increasing problem with the aging population,
and treatments to achieve biological repair or restoration remain a challenge. Cartilage …

OBJECTIVE: Articular chondrocytes respond to chemical and mechanical signals depending
on their zone of origin with respect to distance from the tissue surface. However, little is …

This book covers the latest research and advancements related to articular cartilage in
biology, development, pathology, clinical applications and tissue engineering. The authors …

Despite continuous progress toward tissue engineering of functional articular cartilage,
significant challenges still remain. Advances in morphogens, stem cells, and scaffolds have …

OBJECTIVES: The present study was designed to reveal changes in the collagen network
architecture and collagen content in cartilage during growth and maturation of pigs …

Osteoarthritis is a disease of multifactorial aetiology characterised by progressive
breakdown of articular cartilage. In the early stages of the disease, changes become …

Cartilage defects are notoriously difficult to repair and owing to the long-term prognosis of
osteoarthritis, and a rapidly aging population, a need for new therapies is pressing. Cell …