Progress in corneal wound healing

AV Ljubimov, M Saghizadeh - Progress in retinal and eye research, 2015 - Elsevier
Corneal wound healing is a complex process involving cell death, migration, proliferation,
differentiation, and extracellular matrix remodeling. Many similarities are observed in the …

The knee meniscus: structure–function, pathophysiology, current repair techniques, and prospects for regeneration

EA Makris, P Hadidi, KA Athanasiou - Biomaterials, 2011 - Elsevier
Extensive scientific investigations in recent decades have established the anatomical,
biomechanical, and functional importance that the meniscus holds within the knee joint. As a …

Designing scaffolds for corneal regeneration

M Ahearne, J Fernández‐Pérez… - Advanced Functional …, 2020 - Wiley Online Library
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Innovative human three-dimensional tissue-engineered models as an alternative to animal testing

P Bédard, S Gauvin, K Ferland, C Caneparo, È Pellerin… - Bioengineering, 2020 - mdpi.com
Animal testing has long been used in science to study complex biological phenomena that
cannot be investigated using two-dimensional cell cultures in plastic dishes. With time, it …

Self-organization and the self-assembling process in tissue engineering

KA Athanasiou, R Eswaramoorthy… - Annual review of …, 2013 - annualreviews.org
In recent years, the tissue engineering paradigm has shifted to include a new and growing
subfield of scaffoldless techniques that generate self-organizing and self-assembling …

[HTML][HTML] Corneal regeneration: A review of stromal replacements

S Matthyssen, B Van den Bogerd, SN Dhubhghaill… - Acta biomaterialia, 2018 - Elsevier
Corneal blindness is traditionally treated by transplantation of a donor cornea, or in severe
cases by implantation of an artificial cornea or keratoprosthesis. Due to severe donor …

[HTML][HTML] It is time to crowd your cell culture media–physicochemical considerations with biological consequences

D Tsiapalis, DI Zeugolis - Biomaterials, 2021 - Elsevier
In vivo, the interior and exterior of cells is populated by various macromolecules that create
an extremely crowded milieu. Yet again, in vitro eukaryotic cell culture is conducted in dilute …

Biologicals and biomaterials for corneal regeneration and vision restoration in limbal stem cell deficiency

N Di Girolamo - Advanced Materials, 2024 - Wiley Online Library
The mammalian cornea is decorated with stem cells bestowed with the life‐long task of
renewing the epithelium, provided they remain healthy, functional, and in sufficient numbers …

Alternatives to eye bank native tissue for corneal stromal replacement

I Brunette, CJ Roberts, F Vidal… - Progress in retinal and …, 2017 - Elsevier
Corneal blindness is a major cause of blindness in the world and corneal transplantation is
the only widely accepted treatment to restore sight in these eyes. However, it is becoming …

Macromolecularly crowded in vitro microenvironments accelerate the production of extracellular matrix-rich supramolecular assemblies

P Kumar, A Satyam, X Fan, E Collin, Y Rochev… - Scientific reports, 2015 - nature.com
Therapeutic strategies based on the principles of tissue engineering by self-assembly put
forward the notion that functional regeneration can be achieved by utilising the inherent …