Recent advances in the understanding of enterovirus A71 infection: a focus on neuropathogenesis

HK Tee, MI Zainol, IC Sam, YF Chan - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction: Hand, foot, and mouth disease caused by enterovirus A71 (EV-A71) is more
frequently associated with neurological complications and deaths compared to other …

Hand, foot, and mouth disease: a narrative review

AKC Leung, JM Lam, B Barankin… - Recent Advances in …, 2022 - ingentaconnect.com
Background: Hand, foot, and mouth disease is a common viral disease in childhood.
Because the disease has the potential to reach epidemic levels and mortality is high in some …

Emerging concerns of atypical hand foot and mouth disease caused by recombinant Coxsackievirus A6 variants in Henan, China

S Chen, Y Chen, W Ji, F Wang, X Zhang… - Journal of Medical …, 2023 - Wiley Online Library
An increasing number of studies have reported that atypical hand, foot, and mouth disease
(HFMD) is becoming a new concern for children's health. At present, there is no official …

Phylogenetics and phylogeographic characteristics of coxsackievirus A16 in hand foot and mouth disease and herpangina cases collected in Beijing, China from 2019 …

R Li, C Lin, S Dong, J Li, Z Liang, Y Yang… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Coxsackievirus A16 (CV‐A16) is a significant pathogen responsible for causing
hand foot and mouth disease (HFMD) and herpangina (HA). This study aimed to investigate …

[HTML][HTML] Molecular evolutionary dynamics of coxsackievirus A6 causing hand, foot, and mouth disease from 2021 to 2023 in China: genomic epidemiology study

Y Chen, S Chen, Y Shen, Z Li, X Li… - JMIR Public Health …, 2024 - publichealth.jmir.org
Background Hand, foot, and mouth disease (HFMD) is a global public health concern,
notably within the Asia-Pacific region. Recently, the primary pathogen causing HFMD …

Molecular characterization of echovirus 9 strains isolated from hand-foot-and-mouth disease in Kunming, Yunnan Province, China

M Zhang, W Guo, D Xu, C Feng, G Bao, H Sun… - Scientific Reports, 2022 - nature.com
Abstract Echovirus 9 (E9) belongs to the species Enterovirus B. So far, 12 whole genome
sequences of E9 are available in GenBank. In this study, we determined the whole genomic …

[HTML][HTML] Diagnostic performance of different specimens in detecting enterovirus A71 in children with hand, foot and mouth disease

Y Zhou, C Zhou, K Wang, Q Qiu, Y Cheng, Y Li, P Cui… - Virologica Sinica, 2023 - Elsevier
Hand, foot and mouth disease (HFMD) is a major public health problem among children in
the Asia-Pacific region. The optimal specimen for HFMD virological diagnosis remains …

Completely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection

Z Liu, X Li, X Li, X Yan, Y Tian, Y Zhao, K Liu, P Hao… - mBio, 2025 - journals.asm.org
ABSTRACT The KREMEN1 (KRM1) protein is a cellular receptor for multiple enteroviruses
that cause hand, foot, and mouth disease (HFMD), including coxsackievirus CVA2, CVA3 …

Epidemiological and etiological investigations of hand, foot, and mouth disease in Jiashan, northeastern Zhejiang Province, China, during 2016 to 2022

Y Yuan, Y Chen, J Huang, X Bao, W Shen… - Frontiers in Public …, 2024 - frontiersin.org
Background Hand, foot, and mouth disease (HFMD) is a common infectious disease in
children. Enterovirus A71 (EV71) and coxsackievirus A16 (CA16) have been identified as …

First detection of multiple cases related to CV‐A16 strain of B1c clade in Beijing in 2022

Z Liang, C Lin, D Huo, Y Yang, Z Feng… - Journal of Medical …, 2024 - Wiley Online Library
Abstract Coxsackievirus A16 (CV‐A16) is a significant etiologic agent of hand, foot, and
mouth disease (HFMD) and herpangina (HA), with the capacity to progress to severe …