Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors

B Gonçalves, C Ferreira, CT Alves… - Critical reviews in …, 2016 - Taylor & Francis
Vulvovaginal candidiasis (VVC) is an infection caused by Candida species that affects
millions of women every year. Although Candida albicans is the main cause of VVC, the …

Candida albicans pathogenicity mechanisms

FL Mayer, D Wilson, B Hube - Virulence, 2013 - Taylor & Francis
The polymorphic fungus Candida albicans is a member of the normal human microbiome. In
most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain …

Candida albicans morphogenesis and host defence: discriminating invasion from colonization

NAR Gow, FL Van De Veerdonk, AJP Brown… - Nature reviews …, 2012 - nature.com
Candida albicans is a common fungal pathogen of humans that colonizes the skin and
mucosal surfaces of most healthy individuals. Until recently, little was known about the …

Candidalysin is a fungal peptide toxin critical for mucosal infection

DL Moyes, D Wilson, JP Richardson, S Mogavero… - Nature, 2016 - nature.com
Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial
pathogens which disrupt epithelial barrier function, damage cells and activate or modulate …

Fungi that infect humans

JR Köhler, B Hube, R Puccia, A Casadevall… - Microbiology …, 2017 - Am Soc Microbiol
Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Virulence factors of Candida albicans

RA Calderone, WA Fonzi - Trends in microbiology, 2001 - cell.com
Candidiasis is a common infection of the skin, oral cavity and esophagus, gastrointestinal
tract, vagina and vascular system of humans. Although most infections occur in patients who …

Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

JR Naglik, SJ Challacombe, B Hube - Microbiology and molecular …, 2003 - Am Soc Microbiol
Candida albicans is the most common fungal pathogen of humans and has developed an
extensive repertoire of putative virulence mechanisms that allows successful colonization …

Pathogenesis and treatment of oral candidosis

D Williams, M Lewis - Journal of oral microbiology, 2011 - Taylor & Francis
Oral infections caused by yeast of the genus Candida and particularly Candida albicans
(oral candidoses) have been recognised throughout recorded history. However, since the …

Potential role of phospholipases in virulence and fungal pathogenesis

MA Ghannoum - Clinical microbiology reviews, 2000 - Am Soc Microbiol
Microbial pathogens use a number of genetic strategies to invade the host and cause
infection. These common themes are found throughout microbial systems. Secretion of …