Exploring the role of neurotransmitters in multiple sclerosis: an expanded review

E Akyuz, BR Celik, FS Aslan, H Sahin… - ACS Chemical …, 2023 - ACS Publications
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS). Although emerging evidence has shown that changes in …

Phenolics as GABAA Receptor Ligands: An Updated Review

JL Ríos, GR Schinella, I Moragrega - Molecules, 2022 - mdpi.com
Natural products can act as potential GABA modulators, avoiding the undesirable effects of
traditional pharmacology used for the inhibition of the central nervous system such as …

Piperine improves experimental autoimmune encephalomyelitis (EAE) in lewis rats through its neuroprotective, anti-inflammatory, and antioxidant effects

R Nasrnezhad, S Halalkhor, F Sadeghi… - Molecular …, 2021 - Springer
Inflammation, demyelination, glial activation, and oxidative damage are the most
pathological hallmarks of multiple sclerosis (MS). Piperine, a main bioactive alkaloid of black …

Piperine ameliorated memory impairment and myelin damage in lysolecethin induced hippocampal demyelination

H Roshanbakhsh, ME Salmani, S Dehghan, A Nazari… - Life sciences, 2020 - Elsevier
Aims We still do not have effective treatment for hippocampal demyelination and memory
deficit, the two common comorbidities in multiple sclerosis (MS). This study aimed to assess …

[HTML][HTML] Schema-like learning and memory consolidation acting through myelination

M Hasan, MS Kanna, W Jun, AS Ramkrishnan… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Memory is a dynamic brain function that is continually processed after encoding. Although
psychologic concepts of mental schema are now well established, they have rarely been …

Ultrasound neuromodulation reduces demyelination in a rat model of multiple sclerosis

FY Yang, LH Huang, MT Wu, ZY Pan - International Journal of Molecular …, 2022 - mdpi.com
Microglia, astrocytes, and oligodendrocyte progenitor cells (OPCs) may serve as targets for
remyelination-enhancing therapy. Low-intensity pulsed ultrasound (LIPUS) has been …

Alterations in the behavior, cognitive function, and BDNF level in adult male rats following neonatal blockade of GABA-A receptors

P Naderipoor, M Amani, A Abedi, N Sakhaie… - Brain Research …, 2021 - Elsevier
Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter in the mature
brain. At an early developmental period, it acts in an excitatory manner that influences many …

[HTML][HTML] The interaction between brain and liver regulates lipid metabolism in the TBI pathology

V Palafox-Sánchez, Z Ying, LFF Royes… - … et Biophysica Acta (BBA …, 2021 - Elsevier
To shed light on the impact of systemic physiology on the pathology of traumatic brain injury
(TBI), we examine the effects of TBI (concussive injury) and dietary fructose on critical …

Arbutin improves functional recovery and attenuates glial activation in lysolecethin-induced demyelination model in rat optic chiasm

F Ebrahim-Tabar, A Nazari, M Pouramir… - Molecular …, 2020 - Springer
Neuroinflammation, glial activation, and oxidative injury are the main pathological
mechanisms of demyelination in multiple sclerosis (MS). Arbutin, a natural polyphenol …

Protective effects of hyperbaric oxygen therapy on brain injury by regulating the phosphorylation of Drp1 through ROS/PKC pathway in heatstroke rats

X Ni, J Nie, Q Xie, R Yu, L Su, Z Liu - Cellular and Molecular Neurobiology, 2020 - Springer
This study aimed to elucidate the neurotherapeutic effect of hyperbaric oxygen (HBO) on
brain injury and the potential role of dynamin-related protein 1 (Drp1) and its regulatory …