Existing therapies for epilepsy are primarily symptomatic and target mechanisms of neuronal
transmission in order to restore the excitatory/inhibitory imbalance in the brain after seizures …

CD36 is a highly glycosylated integral membrane protein that belongs to the scavenger
receptor class B family and regulates the pathological progress of metabolic diseases. CD36 …

Background The ketogenic diet (KD) is increasingly used to treat drug-resistant epilepsy
because of its favorable effect on seizure reduction. Patients with mitochondrial diseases …

We evaluated the effects of cannabidiol (CBD) on seizures and peroxisome proliferator-
activated receptor gamma (PPARγ) levels in an animal model of temporal lobe epilepsy …

Neurocognitive impairment refers to a spectrum of disorders characterized by a decline in
cognitive functions such as memory, attention, and problem-solving, which are often linked …

In mammals, peroxisome proliferators activated receptors (PPARs), the nuclear hormone
receptors, have been reported to be involved in seizure control. Selective agonists and …

The peroxisome proliferator-activated receptor gamma (PPARγ), which belongs to the family
of nuclear receptors, has been mainly studied as an important factor in metabolic disorders …

Compounds present in Cannabis sativa L. preparations have recently attracted much
attention in the treatment of drug-resistant epilepsy. Here, we screened two olive oil extracts …

Abrupt withdrawal from antiepileptic drugs is followed by increased occurrence of epileptic
seizures, a phenomenon known as the “rebound effect”. By stopping treatment with …

Introduction Mitochondrial dysfunction is a common denominator of neuroinflammation
recognized by neuronal oxidative stress-mediated apoptosis that is well recognized by …