Rett syndrome (RTT) is a neurological disorder caused by mutations in the X-linked gene
methyl-CpG-binding protein 2 (MECP2), a ubiquitously expressed transcriptional regulator …

Zebrafish are increasingly being utilized as a model system to investigate the function of the
growing list of risk genes associated with neurodevelopmental disorders. This is due in large …

Adult zebrafish are robustly social animals whereas larva is not. We designed an assay to
determine at what stage of development zebrafish begin to interact with and prefer other fish …

Movement disorders can be primarily divided into hypokinetic and hyperkinetic. Most of the
hypokinetic syndromes are associated with the neurodegenerative disorder Parkinson's …

For the past few years there has been an exponential increase in the use of animal models
to confirm the pathogenicity of candidate disease-causing genetic variants found in patients …

Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) are two
debilitating neurodevelopmental disorders. The former is associated with social impairments …

Rett syndrome (RTT) is a severe and progressive neurological disorder, which mainly affects
young females. Mutations of the methyl-CpG binding protein 2 (MECP2) gene are the most …

De novo and inherited rare genetic disorders (RGDs) are a major cause of human morbidity,
frequently involving neuropsychiatric symptoms. Recent advances in genomic technologies …

Autism spectrum disorder (ASD) refers to a complicated range of childhood
neurodevelopmental disorders which can occur via genetic or non-genetic factors. Clinically …

Neurodevelopmental disorders (NDDs) caused by aberrant brain growth and development
are life-long, debilitating illnesses that markedly impair the quality of life. Animal models are …