Circulating tumor DNA in B-cell lymphoma: technical advances, clinical applications, and perspectives for translational research

EM Lauer, J Mutter, F Scherer - Leukemia, 2022 - nature.com
Noninvasive disease monitoring and risk stratification by circulating tumor DNA (ctDNA)
profiling has become a potential novel strategy for patient management in B-cell lymphoma …

PET/CT in non-Hodgkin lymphoma: an update

L Zanoni, D Bezzi, C Nanni, A Paccagnella… - Seminars in nuclear …, 2023 - Elsevier
Non-Hodgkin lymphomas represents a heterogeneous group of lymphoproliferative
disorders characterized by different clinical courses, varying from indolent to highly …

Axicabtagene ciloleucel as first-line therapy in high-risk large B-cell lymphoma: the phase 2 ZUMA-12 trial

SS Neelapu, M Dickinson, J Munoz, ML Ulrickson… - Nature medicine, 2022 - nature.com
High-risk large B-cell lymphoma (LBCL) has poor outcomes with standard first-line
chemoimmunotherapy. In the phase 2, multicenter, single-arm ZUMA-12 study …

Circulating tumor DNA measurements as early outcome predictors in diffuse large B-cell lymphoma

DM Kurtz, F Scherer, MC Jin, J Soo… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Outcomes for patients with diffuse large B-cell lymphoma remain heterogeneous,
with existing methods failing to consistently predict treatment failure. We examined the …

18F-FDG PET dissemination features in diffuse large B-cell lymphoma are predictive of outcome

AS Cottereau, C Nioche, AS Dirand… - Journal of Nuclear …, 2020 - Soc Nuclear Med
We assessed the predictive value of new radiomic features characterizing lesion
dissemination in baseline 18F-FDG PET and tested whether combining them with baseline …

FDG‐PET/CT in the management of lymphomas: current status and future directions

TC El‐Galaly, D Villa, LC Gormsen… - Journal of internal …, 2018 - Wiley Online Library
Abstract FDG‐PET/CT is the current state‐of‐the‐art imaging in lymphoma and plays a
central role in treatment decisions. At diagnosis, accurate staging is crucial for appropriate …

PET molecular imaging: a holistic review of current practice and emerging perspectives for diagnosis, therapeutic evaluation and prognosis in clinical oncology

V Duclos, A Iep, L Gomez, L Goldfarb… - International journal of …, 2021 - mdpi.com
PET/CT molecular imaging has been imposed in clinical oncological practice over the past
20 years, driven by its two well-grounded foundations: quantification and radiolabeled …

Obinutuzumab vs rituximab for advanced DLBCL: a PET-guided and randomized phase 3 study by LYSA

S Le Gouill, H Ghesquieres, L Obéric… - Blood, The Journal …, 2021 - ashpublications.org
Rituximab plus polychemotherapy is the standard of care in diffuse large B-cell lymphoma
(DLBCL). GAINED, a randomized phase 3 trial, compared obinutuzumab to rituximab …

Prognostic value of interim FDG-PET in diffuse large cell lymphoma: results from the CALGB 50303 Clinical Trial

H Schöder, MYC Polley, MV Knopp… - Blood, The Journal …, 2020 - ashpublications.org
As part of a randomized, prospective clinical trial in large cell lymphoma, we conducted
serial fluorodeoxyglucose positron emission tomography (FDG-PET) at baseline, after 2 …

The role of PET in the first-line treatment of the most common subtypes of non-Hodgkin lymphoma

SF Barrington, J Trotman - The Lancet Haematology, 2021 - thelancet.com
This Review focuses on the use of 18 F-fluorodeoxyglucose (18 F-FDG) PET in the
assessment of diffuse large B-cell lymphoma, follicular lymphoma, and peripheral T-cell …