Microbiomes are integral components of diverse ecosystems, and increasingly recognized
for their roles in the health of humans, animals, plants, and other hosts. Given their …

Dietary patterns, microbiome dysbiosis, and gut microbial metabolites (GMMs) have a
pivotal role in the homeostasis of intestinal epithelial cells and in disease progression, such …

Objective The intestinal flora of gut microbiota in obese Chinese children and adolescents
with and without insulin resistance (IR) was analyzed, as well as associations between the …

Background Diabetic kidney disease (DKD) is the most common cause of end-stage renal
disease (ESRD), but the mechanism between DKD and ESRD remains unclear. Some …

New Findings What is the topic of this review? The Zucker Diabetic‐Sprague Dawley
(ZDSD) rat is in the early adoption phase of use by researchers in the fields of diabetes …

Background Evidence indicates a link between the pathogenesis of type 1 diabetes (T1D)
and the gut microbiome. However, the regulation of microbial metabolic pathways and the …

Insulin resistance has wide-ranging effects on metabolism, but there are knowledge gaps
regarding the tissue origins of systemic metabolite patterns and how patterns are altered by …

The gut microbiome has the potential to create or modify xenometabolites (ie, nonhost-
derived metabolites) through de novo synthesis or modification of exogenous and …

In recent years, bariatric surgery has emerged as a promising treatment for type 2 diabetes.
Bariatric surgery is known to cause alterations in the relative abundance and composition of …

Deterioration in glucose homeostasis has been associated with intestinal dysbiosis, but it is
not known how metabolic dysregulation alters the gastrointestinal environment. We …