Contribution of semen to early embryo development: fertilization and beyond

M Vallet-Buisan, R Mecca, C Jones… - Human …, 2023 - academic.oup.com
BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …

[HTML][HTML] Sperm DNA fragmentation: a new guideline for clinicians

A Agarwal, A Majzoub, S Baskaran… - The world journal of …, 2020 - ncbi.nlm.nih.gov
Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Evidence-based guideline: unexplained infertility

Guideline Group on Unexplained Infertility… - Human …, 2023 - academic.oup.com
STUDY QUESTION What is the recommended management for couples presenting with
unexplained infertility (UI), based on the best available evidence in the literature …

Clinical implications of sperm DNA damage in IVF and ICSI: updated systematic review and meta‐analysis

J Ribas‐Maynou, M Yeste, N Becerra‐Tomás… - Biological …, 2021 - Wiley Online Library
The clinical effect of sperm DNA damage in assisted reproduction has been a controversial
topic during recent decades, leading to a variety of clinical practice recommendations. While …

Genetic mechanisms of fertilization failure and early embryonic arrest: a comprehensive review

Y Wei, J Wang, R Qu, W Zhang, Y Tan… - Human …, 2024 - academic.oup.com
BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

Sperm quality metrics were improved by a biomimetic microfluidic selection platform compared to swim-up methods

SA Vasilescu, L Ding, FY Parast, R Nosrati… - Microsystems & …, 2023 - nature.com
Sperm selection is an essential component of all assisted reproductive treatments (ARTs)
and is by far the most neglected step in the ART workflow in regard to technological …

[HTML][HTML] Oocyte ability to repair sperm DNA fragmentation: the impact of maternal age on intracytoplasmic sperm injection outcomes

AS Setti, DPAF Braga, RR Provenza, A Iaconelli Jr… - Fertility and …, 2021 - Elsevier
Objective To study the impact of sperm DNA fragmentation (SDF) on clinical outcomes of
assisted reproductive technology in women with different age ranges. Design Historical …

An update on clinical and surgical interventions to reduce sperm DNA fragmentation in infertile men

SC Esteves, D Santi, M Simoni - Andrology, 2020 - Wiley Online Library
Background Sperm chromatin integrity is essential for normal embryo development and
pregnancy outcome. Sperm DNA fragmentation (SDF) testing constitutes a diagnostic tool to …

Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentation

S Dutta, R Henkel, A Agarwal - Andrologia, 2021 - Wiley Online Library
Male infertility has a complex etiology, and many times, the cause is unknown. While routine
semen analysis provides an overview of basic semen parameters, such as sperm …

The impact of a very short abstinence period on conventional sperm parameters and sperm DNA fragmentation: a systematic review and meta-analysis

F Barbagallo, R Cannarella, A Crafa, C Manna… - Journal of Clinical …, 2022 - mdpi.com
Purpose: In recent years, a growing number of studies have supported the beneficial effects
of a very short abstinence period on sperm parameters, especially in patients with …