A comprehensive account on recent progress in pharmacological activities of benzimidazole derivatives

SR Brishty, MJ Hossain, MU Khandaker… - Frontiers in …, 2021 - frontiersin.org
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …

Zinc complexes with nitrogen donor ligands as anticancer agents

M Porchia, M Pellei, F Del Bello, C Santini - Molecules, 2020 - mdpi.com
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Benzimidazole based derivatives as anticancer agents: Structure activity relationship analysis for various targets

G Satija, B Sharma, A Madan, A Iqubal… - Journal of …, 2022 - Wiley Online Library
Benzimidazole, the benzo derivative of imidazole, is a class of bicyclic aromatic organic
compound consisting of six‐membered benzene ring fused to five‐membered imidazole at 4 …

First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity

D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

[HTML][HTML] An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds

HE Hashem, Y El Bakri - Arabian Journal of Chemistry, 2021 - Elsevier
Benzimidazole, a benzene-fused heterocyclic compound, has acquired significant attention
in the field of contemporary medicinal chemistry because of its wide array of …

Zinc coordination compounds with benzimidazole derivatives: Synthesis, structure, antimicrobial activity and potential anticancer application

A Raducka, M Świątkowski, I Korona-Głowniak… - International Journal of …, 2022 - mdpi.com
Developing new, smart drugs with the anticancer activity is crucial, especially for cancers,
which cause the highest mortality in humans. In this paper we describe a series of …

[HTML][HTML] Design, synthesis, characterization of zirconium (IV), cadmium (II) and iron (III) complexes derived from Schiff base 2-aminomethylbenzimidazole, 2 …

AN Al-Hakimi, F Alminderej, L Aroua, SK Alhag… - Arabian Journal of …, 2020 - Elsevier
Abstract (E)-1-((((1H-benzo [d] imidazol-2-yl) methyl) imino) methyl) naphthalen-2-ol, ligand
was synthesized by condensation of (1H-benzo [d] imidazol-2-yl) methanamine, with 2 …

Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy

DA Guk, OO Krasnovskaya… - Russian Chemical …, 2021 - iopscience.iop.org
The review summarizes the data on the structures and methods for the synthesis of
compounds with anticancer activity based on biogenic metals, which can replace platinum …

Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria

EME Dokla, NS Abutaleb, SN Milik, D Li… - European Journal of …, 2020 - Elsevier
Gram-negative bacteria pose a distinctive risk worldwide, especially with the evolution of
major resistance to carbapenems, fluoroquinolones and colistin. Therefore, development of …

Synthesis and anticancer properties of novel hydrazone derivatives incorporating pyridine and isatin moieties

Z Zebbiche, S Tekin, H Küçükbay, F Yüksel… - Archiv Der …, 2021 - Wiley Online Library
Nine novel hydrazone derivatives (4a–i) incorporating pyridine and isatin moieties were
synthesized through one‐pot, four‐component heterocyclic condensation reactions. The …